- Basic information
- CohesinDB ID: CDBP00416815
- Locus: chr21-32043695-32044823
-
Data sourse: GSE67783, GSE86191, GSE116868, GSE206145-NatGen2015, ENCSR153HNT
-
Cell type: Fibroblast, HCT-116, MB157, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SA2,SMC1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
66% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 56%,
"9_Het": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: XBP1, SNAPC4, FOXA1, SUZ12, ZNF90, ATF3, LMO2, ESR1, OCA2, MED26, USF2, CTCF, MNT, PAX8, ZNF528, EED, POU2F2, NANOG, BRD1, CHD8, MYCN, POU5F1, ZNF263, ID3, KDM4C, ZBTB48, STAT1, MYC, GRHL3, GABPA, APC, STAT3, HNRNPH1, DNMT3B, ARNTL, SRSF3, CREB1, EZH2, GRHL2, SPI1, IRF1, SSRP1, GATA2, SIX2, RELB, HCFC1R1, RUNX1, SMC1A, CRY1, ZFX, POU4F2, TET2, ZNF384, OSR2, ARNT, CDK8, ZNF22, MAFK, GSPT2, NR4A1, TCF3, AATF, SMC3, STAG1, TRP47, PPARG, FOXA2, TBL1X, GTF2B, WT1, BCL3, KDM1A, YY1, RELA, SP140, HIF1A, TAL1, MAX, ZNF143, PLAG1, NCOA3, NR2F1, TP53, NFKB1, MYOD1, AR, EGLN2, HSF1, NCOR1, NOTCH3, JUND, BRD4, NR1H3, CLOCK, MAZ
- Target gene symbol (double-evidenced CRMs): EVA1C
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops