- Basic information
- CohesinDB ID: CDBP00416822
- Locus: chr21-32067081-32068048
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Data sourse: GSE67783, GSE86191, GSE83726, GSE111537, GSE25021
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Cell type: RH4, HCT-116, Hep-G2, OCI-AML-3, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
66% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 67%,
"14_ReprPCWk": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: XBP1, FOXA1, PBX2, ZFHX2, ZNF273, JMJD1C, KLF5, ESR1, PITX3, CTCF, TCF12, BAF155, EP300, TRIM24, CREB3, SOX6, ZNF350, TEAD4, PDX1, TFAP2C, BRD1, ZSCAN5D, POU5F1, MYCN, RUNX1T1, ZBTB48, ZSCAN5A, DUX4, ZNF205, ERG, MYC, RAD21, GRHL3, NKX2-1, PRDM14, RCOR1, NR2F6, CEBPB, ESRRA, EZH2, GRHL2, EBF3, SPI1, GATA2, NCOA2, RUNX1, SMC1A, EZH2phosphoT487, ZFX, TET2, ERG3, TWIST1, PRDM10, ARNT, MED1, DIDO1, L3MBTL2, SETDB1, BCL11A, SMC3, STAG1, CBFA2T2, FOXA2, CREM, CHD2, WT1, FOXF1, HOXB13, KDM1A, YY1, RELA, NEUROD1, ISL1, SP140, TCF4, HIF1A, OTX2, GATA3, NRIP1, GATA1, HAND2, PLAG1, NEUROG2, ZNF334, EGR2, PHOX2B, AR, MAML3, EGR1, RNF2, NOTCH3, BRD4, JUND, MAZ, TBX2
- Target gene symbol (double-evidenced CRMs): HUNK,MIS18A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops