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Basic information

CohesinDB ID: CDBP00416823

Locus: chr21-32070620-32071627

Data sourse: GSE206145-GSE177045, ENCSR000BLY, ENCSR879KXD, ENCSR000EHW, GSE206145-NatGen2015, ENCSR000EHX

Cell type: K-562, Fibroblast, MCF-7, SK-N-SH

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: Mau2,SMC3,Rad21,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 66% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 70%, "14_ReprPCWk": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: XBP1, FOXA1, PBX2, ZFHX2, ZNF273, JMJD1C, KLF5, ESR1, PITX3, CTCF, TCF12, BAF155, EP300, TRIM24, CREB3, SOX6, ZNF350, TEAD4, PDX1, TFAP2C, BRD1, ZSCAN5D, POU5F1, MYCN, RUNX1T1, ZBTB48, ZSCAN5A, DUX4, ZNF205, ERG, MYC, RAD21, GRHL3, NKX2-1, PRDM14, RCOR1, NR2F6, CEBPB, ESRRA, EZH2, GRHL2, EBF3, SPI1, GATA2, NCOA2, RUNX1, SMC1A, EZH2phosphoT487, ZFX, TET2, ERG3, TWIST1, PRDM10, ARNT, MED1, DIDO1, L3MBTL2, SETDB1, BCL11A, SMC3, STAG1, CBFA2T2, FOXA2, CREM, CHD2, WT1, FOXF1, HOXB13, KDM1A, YY1, RELA, NEUROD1, ISL1, SP140, TCF4, HIF1A, OTX2, GATA3, NRIP1, GATA1, HAND2, PLAG1, NEUROG2, ZNF334, EGR2, PHOX2B, AR, MAML3, EGR1, RNF2, NOTCH3, BRD4, JUND, MAZ, TBX2

Target gene symbol (double-evidenced CRMs): HUNK,MIS18A

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000142149, ENSG00000159055,

eachgene

Deatailed information for cohesin site CDBP00416823