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Basic information

CohesinDB ID: CDBP00416824

Locus: chr21-32073717-32074345

Data sourse: GSE206145-NatGen2015, GSE67783, ENCSR153HNT, GSE86191

Cell type: K-562, Fibroblast, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 66% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 73%, "14_ReprPCWk": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, ZNF426, ZNF697, SOX2, XBP1, ZNF101, FOXA1, SUZ12, ZFHX2, ATF3, BMI1, ZFP64, CHD7, PRDM12, CBFB, PAX5, TP63, ZSCAN4, ZNF629, RBM39, ETV1, LMO2, ESR1, PITX3, CTCF, TCF12, ZNF577, BAF155, EP300, GATA6, TEAD4, ZNF555, PDX1, TFAP2C, CHD8, MYCN, ZNF263, POU5F1, TOP2A, ZBTB17, DUX4, ZBTB48, STAT1, ZSCAN5A, ZNF433, DDX5, ERG2, TBP, ERG, OGG1, ZBTB8A, MYC, EZH1, SMARCA4, ONECUT1, RAD21, GRHL3, GABPA, STAT3, XRCC5, NKX3-1, RCOR1, ARNTL, NR3C1, CREB1, ZBTB11, EZH2, EBF3, SPI1, ZNF202, GATA2, MXD3, FLI1, MXI1, RUNX1, SMC1A, NKX2-2, SIRT6, EZH2phosphoT487, ZFX, SMAD3, ERG3, CBX8, TWIST1, ZNF384, ARNT, ZNF781, ZNF518A, ETV6, MED1, ZEB1, MYB, ZNF680, ZMYM3, PIAS1, SMAD1, USF1, ASH2L, HNRNPLL, FOXP1, AATF, ZNF623, SMC3, ZNF34, STAG1, NFATC3, ZNF394, TRP47, FOXA2, TBL1X, CHD2, WT1, HOXB13, KDM1A, YY1, RELA, TARDBP, ISL1, SP140, ZFP36, HIF1A, TCF4, GATA3, MAX, NRIP1, ZNF143, GATA1, HAND2, PLAG1, TLE3, ZFP69B, CBX2, NCOA3, NR2F1, TP53, ZNF334, ZSCAN22, EGR2, PHOX2B, ZNF140, ARRB1, PAX3-FOXO1, AR, RXR, MAML3, HEXIM1, EGR1, HSF1, RNF2, NOTCH3, BRD4, ILF3, CLOCK, MAZ

Target gene symbol (double-evidenced CRMs): MIS18A,HUNK

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 6

Related genes and loops

Related gene: ENSG00000142149, ENSG00000159055,

eachgene

Deatailed information for cohesin site CDBP00416824