- Basic information
- CohesinDB ID: CDBP00416830
- Locus: chr21-32084044-32084525
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Data sourse: GSE206145-NatGen2015, GSE120943
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Cell type: Fibroblast, Monocytes
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
66% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 78%,
"14_ReprPCWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF660, NME2, PATZ1, FOXA1, ZFHX2, NFIC, ZBTB44, CHD7, MZF1, ESR1, PITX3, CTCF, TCF12, JUN, EP300, TEAD4, CHD8, BRD3, ZNF263, ZNF317, ZBTB17, ZBTB48, DDX5, TBP, ERG, OGG1, SMARCA4, RAD21, GRHL3, GABPA, STAT3, RCOR1, ARNTL, EZH2, FEZF1, EBF3, GATA2, SIX2, FLI1, MRTFB, ZNF554, EZH2phosphoT487, NKX2-2, ZFX, POU4F2, ERG3, TWIST1, PRDM10, ZNF35, OSR2, ZNF184, ZEB2, FOS, MED1, GSPT2, ZNF479, PRDM6, SMC3, FOXA2, CHD2, ZNF600, ZNF692, ZSCAN16, ZNF30, HOXB13, KDM1A, YY1, RELA, NEUROD1, JUNB, ISL1, HIF1A, OTX2, GATA3, ZNF143, GATA1, HAND2, ZNF334, NFKB1, MYOD1, PHOX2B, AR, PAX3-FOXO1, ZNF366, RNF2, NCOR1, BRD4, MAZ, TBX2, FOSL2
- Target gene symbol (double-evidenced CRMs): CFAP298,HUNK,MIS18A,TIAM1,SYNJ1,CFAP298-TCP10L
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000156299,
ENSG00000142149,
ENSG00000159055,
ENSG00000265590,
ENSG00000159079,
ENSG00000159082,
- Related loop:
chr21:31375000-31400000~~chr21:32075000-32100000,
chr21:31825000-31850000~~chr21:32075000-32100000,
chr21:31850000-31875000~~chr21:32075000-32100000,
chr21:31950000-31975000~~chr21:32075000-32100000,
chr21:31975000-32000000~~chr21:32075000-32100000,
chr21:32075000-32100000~~chr21:32200000-32225000,
chr21:32075000-32100000~~chr21:32225000-32250000,
chr21:32075000-32100000~~chr21:32250000-32275000,
chr21:32075000-32100000~~chr21:32600000-32625000,