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Basic information

CohesinDB ID: CDBP00416834

Locus: chr21-32095485-32097938

Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE104888, ENCSR230ZWH, GSE72082, ENCSR000BSB, GSE126634, GSE116868, ENCSR000EGW, ENCSR000BLY, GSE105028, GSE121355, GSE103477, GSE111537, GSE131606, GSE108869, ENCSR000EDW, GSE25021, ENCSR000BUC, GSE115602, ENCSR000BTU, GSE93080, ENCSR000DZP, ENCSR000EAC, GSE143937, ENCSR000BKV, GSE115250, GSE138405, GSE67783, GSE86191, GSE76893, GSE101921, GSE152721, GSE206145-NatGen2015, GSE112028, GSE130135, ENCSR703TNG, GSE106870, GSE116344, GSE145327, GSE94872, ENCSR000EEG, ENCSR338DUC, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, GSE206145, ENCSR000ECE, ENCSR000BMY, ENCSR000EHX, ENCSR767DFK, GSE97394, GSE55407, ENCSR000BTQ, GSE105004, ENCSR167MTG, GSE131956, GSE110061, GSE129526, GSE111913, GSE155324, ENCSR335RKQ, ENCSR054FKH, ENCSR000EDE, GSE68388, GSE83726, GSE126990, GSE50893, ENCSR000ECS

Cell type: MDM, RH4, GM10847, GM2610, CVB-hiPSC, GM19240, HSPC, CVI-hiPSC, Liver, TC-32, HuCC-T1, H9-hESC, RPE, GM2630, Fibroblast, Ishikawa, GM12890, HeLa-S3, GM2255, K-562, GM18486, DKO, GM18526, H1-hESC, SNYDER, GM18505, MB157, Lymphoblast, GM12878, GM12891, GM2588, GBM39, SK-N-SH, GM19239, HeLa-Tet-On, GM19193, RT-112, THP-1, GM19099, HUES64, MCF-7, GM12892, Hela-Kyoto, HCT-116, HEK293T, Hep-G2, A-549, HUVEC, HCAEC, GM19238, HeLa, OCI-AML-3, HAP1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 36% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.400

Subunit: SA1,Rad21,SMC1,SA2,SMC3

CTCF binding site: CTCF CTCF motif: True

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 66% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 54%, "14_ReprPCWk": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RELA, ZNF384, OGG1, SP140, ZBTB48, DDX5

Target gene symbol (double-evidenced CRMs): SYNJ1,MIS18A,CFAP298-TCP10L,TIAM1,HUNK,CFAP298

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000156299, ENSG00000142149, ENSG00000159055, ENSG00000265590, ENSG00000159079, ENSG00000159082,

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Deatailed information for cohesin site CDBP00416834