- Basic information
- CohesinDB ID: CDBP00416836
- Locus: chr21-32099703-32101172
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE72082, ENCSR000BSB, ENCSR000EGW, ENCSR000BLY, GSE105028, GSE121355, GSE131606, GSE25021, ENCSR000EFJ, ENCSR000BTU, GSE67783, ENCSR000BKV, GSE115250, GSE138405, GSE86191, GSE206145-NatGen2015, GSE130135, ENCSR703TNG, GSE106870, GSE116344, GSE145327, ENCSR000BLS, ENCSR000EHW, GSE206145, ENCSR000ECE, ENCSR000BMY, ENCSR000EHX, GSE97394, ENCSR000BTQ, ENCSR167MTG, GSE110061, GSE129526, ENCSR000HPG, ENCSR054FKH, GSE68388, GSE83726, GSE126990, GSE50893
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Cell type: RH4, GM2610, CVB-hiPSC, TC-32, HuCC-T1, H9-hESC, RPE, GM2630, Fibroblast, Ishikawa, IMR-90, K-562, DKO, H1-hESC, GM12878, SK-N-SH, HUES64, MCF-7, GM12892, Hela-Kyoto, HCT-116, HEK293T, Hep-G2, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 16% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.733
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
66% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 58%,
"14_ReprPCWk": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, LCORL, SOX2, FOXA1, SUZ12, ZFHX2, NFIC, CHD7, JMJD1C, MYOG, ESR1, OCA2, CTCF, TCF12, JUN, EP300, TFAP2C, GLIS1, NANOG, POU2F2, CHD8, ZSCAN5D, MYCN, POU5F1, TOP2A, ZBTB17, ZBTB48, ZSCAN5A, STAT1, ERG2, TBP, SMARCA4, RAD21, NKX2-1, XRCC5, ZNF398, PRDM14, HNRNPH1, CREB1, EZH2, GRHL2, EBF3, GATA2, HCFC1R1, MAFG, SMC1A, ZFX, SMAD3, TET2, ERG3, SMARCC1, CREBBP, ZNF184, NFIB, ARNT, ATF2, PRDM9, FOS, PIAS1, SMAD1, C11orf30, MAFK, ZBTB7A, FOXP1, SMC3, STAG1, PPARG, MAFF, WT1, ZNF662, HOXB13, RELA, TARDBP, NEUROD1, JUNB, SP140, ZIC2, ZFP36, OTX2, GATA3, MAX, GATA1, NCOA3, ZNF544, ZNF334, BCL6B, MYOD1, EGR2, T, AR, PAX3-FOXO1, EGLN2, ZBTB42, HSF1, BRD4, JUND, MAZ, ZNF440, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): CFAP298,SYNJ1,HUNK,MIS18A,CFAP298-TCP10L,TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000156299,
ENSG00000142149,
ENSG00000159055,
ENSG00000265590,
ENSG00000159079,
ENSG00000159082,
- Related loop:
chr21:27500000-27525000~~chr21:32100000-32125000,
chr21:31375000-31400000~~chr21:32075000-32100000,
chr21:31780114-31782449~~chr21:32099458-32101030,
chr21:31780165-31781913~~chr21:32099650-32100808,
chr21:31825000-31850000~~chr21:32075000-32100000,
chr21:31850000-31875000~~chr21:32075000-32100000,
chr21:31950000-31975000~~chr21:32075000-32100000,
chr21:31975000-32000000~~chr21:32075000-32100000,
chr21:32075000-32100000~~chr21:32200000-32225000,
chr21:32075000-32100000~~chr21:32225000-32250000,
chr21:32075000-32100000~~chr21:32250000-32275000,
chr21:32075000-32100000~~chr21:32600000-32625000,
chr21:32095899-32097665~~chr21:32142694-32144879,
chr21:32095899-32097665~~chr21:32256342-32259326,
chr21:32095914-32097481~~chr21:32256462-32259302,
chr21:32095923-32097744~~chr21:32257185-32259313,
chr21:32095946-32097766~~chr21:32256274-32259275,
chr21:32095947-32097429~~chr21:32257192-32259306,
chr21:32095949-32097315~~chr21:32257417-32259304,
chr21:32095949-32097664~~chr21:32256341-32259331,
chr21:32095950-32097502~~chr21:32257195-32259363,
chr21:32095976-32097575~~chr21:32599358-32601801,
chr21:32095978-32097865~~chr21:32256367-32259995,
chr21:32095998-32097302~~chr21:32257467-32259276,
chr21:32096061-32097312~~chr21:32257419-32259297,
chr21:32100000-32125000~~chr21:32250000-32275000,