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Basic information

CohesinDB ID: CDBP00416837

Locus: chr21-32102092-32102845

Data sourse: GSE206145-NatGen2015, GSE67783

Cell type: Fibroblast, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Mau2,SA1,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 66% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 69%, "14_ReprPCWk": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, LCORL, SOX2, FOXA1, SUZ12, ZFHX2, NFIC, CHD7, JMJD1C, MYOG, ESR1, OCA2, CTCF, TCF12, JUN, EP300, TFAP2C, GLIS1, NANOG, POU2F2, CHD8, ZSCAN5D, MYCN, POU5F1, TOP2A, ZBTB17, ZBTB48, ZSCAN5A, STAT1, ERG2, TBP, SMARCA4, RAD21, NKX2-1, XRCC5, ZNF398, PRDM14, HNRNPH1, CREB1, EZH2, GRHL2, EBF3, GATA2, HCFC1R1, MAFG, SMC1A, ZFX, SMAD3, TET2, ERG3, SMARCC1, CREBBP, ZNF184, NFIB, ARNT, ATF2, PRDM9, FOS, PIAS1, SMAD1, C11orf30, MAFK, ZBTB7A, FOXP1, SMC3, STAG1, PPARG, MAFF, WT1, ZNF662, HOXB13, RELA, TARDBP, NEUROD1, JUNB, SP140, ZIC2, ZFP36, OTX2, GATA3, MAX, GATA1, NCOA3, ZNF544, ZNF334, BCL6B, MYOD1, EGR2, T, AR, PAX3-FOXO1, EGLN2, ZBTB42, HSF1, BRD4, JUND, MAZ, ZNF440, ZNF316, FOSL2

Target gene symbol (double-evidenced CRMs): MIS18A

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000159055,

eachgene

Deatailed information for cohesin site CDBP00416837