- Basic information
- CohesinDB ID: CDBP00416847
- Locus: chr21-32134466-32136596
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Data sourse: ENCSR000BLD, GSE93080, ENCSR000DZP, ENCSR000EAC, GSE72082, ENCSR000BKV, GSE131956, GSE138405, GSE86191, GSE129526, ENCSR000BLY, GSE105028, GSE206145-NatGen2015, ENCSR000ECE, ENCSR000BMY, ENCSR000EHX, GSE83726, GSE25021, GSE50893, GSE97394
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Cell type: RH4, GM2610, GM19240, H9-hESC, GM2630, Fibroblast, GM12890, K-562, H1-hESC, SNYDER, GM18505, GM12878, GM2588, GBM39, SK-N-SH, HUES64, MCF-7, GM12892, Hela-Kyoto, HCT-116, Hep-G2
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 11% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.767
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
66% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 45%,
"7_Enh": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, HMG20A, SOX2, MEIS2, FOXA1, PBX2, ZNF596, ZFHX2, HDGF, TSC22D4, ATF3, NFIC, RUNX3, PRDM1, CHD7, CBFB, DPF1, SMARCE1, ZNF189, PAX5, MITF, ZNF736, BACH2, TEAD1, TRIM28, ZNF573, ETV1, BCLAF1, NFE2L2, LMO2, ESR1, MED26, USF2, ZFP91, JUN, CTCF, TCF12, BAF155, EP300, E4F1, MNT, KLF1, SOX5, DPF2, TRIM24, IRF4, SOX6, RAD51, E2F1, ZNF528, TEAD4, FOXA3, EHMT2, TFAP2C, EED, RBPJ, GLIS1, PDX1, POU2F2, CHD8, BRD1, ZNF263, MYCN, TOP2A, POU5F1, CTBP1, ZSCAN21, ERF, ZBTB48, ZNF317, STAT1, DUX4, SRF, DDX5, SAP130, ARID3A, ERG2, TBP, ERG, ASCL1, MYC, SMARCA4, HOMEZ, ARID1B, RAD21, GRHL3, RXRA, NKX2-1, FOXK2, GABPA, STAT3, XRCC5, IKZF1, NFE2, RCOR1, ZNF639, ARNTL, ZNF750, ESRRA, NR3C1, CEBPB, KMT2A, CREB1, CCAR2, EZH2, TBL1XR1, GRHL2, EBF3, NFE2L1, SPI1, ZNF664, HDAC2, GATA2, ZNF644, SIX2, FLI1, SMARCA5, NFIL3, NFYB, MRTFB, NCOA2, ZIM3, ATF1, RUNX1, NFATC1, MAFG, BCL6, CEBPA, EZH2phosphoT487, NKX2-2, MTA3, SOX13, ZFX, SIN3A, SMC1A, SMAD3, PCBP2, ZNF770, ERG3, SMARCC1, TWIST1, MEF2A, CREBBP, NFYC, ZBTB2, RUNX2, ARNT, NRF1, BACH1, PBX4, ZNF48, ATF2, SMAD4, PBX3, MAFB, FOXM1, FOS, ETV6, MED1, ICE2, TEAD3, PML, ZEB1, MYB, SCRT2, ZMYM3, PIAS1, ZNF3, KLF9, ZNF41, L3MBTL2, C11orf30, SETDB1, NCOA1, STAT5A, USF1, BCL11A, TFAP2A, MAFK, HNF4A, GSPT2, SP1, NIPBL, ARID2, ZBTB7A, RBM25, ASH2L, BCOR, FOXP1, TCF3, NCOR2, STAG2, STAG1, ZNF283, MEF2B, ZNF316, FOXA2, CBX3, EBF1, RBBP5, SS18, CREM, MIER2, ZNF692, ZBED1, MAFF, WT1, MEIS1, FOXF1, GTF2B, MEF2C, CDK9, HOXB13, BCL3, KDM1A, YY1, RELA, NEUROD1, JUNB, CHAMP1, BRG1, SP140, ZFP36, HIF1A, ZIC2, SKIL, GATA3, BATF, TAL1, MAX, NRIP1, ZNF143, MTA1, GATA1, SPIB, PLAG1, KLF4, NR2F2, ZNF512, TCF7L2, KDM5B, TP53, PKNOX1, MED, ZNF334, NFKB1, EGR2, PHOX2B, BRD2, BHLHE40, AR, ZNF366, ZBTB26, RNF2, HSF1, BRD4, ILF3, JUND, SCRT1, MAZ, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): MIS18A,TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops