- Basic information
- CohesinDB ID: CDBP00416850
- Locus: chr21-32143117-32144304
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Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE72082, ENCSR000BLY, GSE105028, GSE131606, GSE25021, ENCSR917QNE, ENCSR000BKV, GSE86191, GSE206145-NatGen2015, ENCSR703TNG, GSE106870, GSE145327, ENCSR879KXD, ENCSR000BLS, ENCSR000ECE, ENCSR000BMY, ENCSR000EHX, GSE97394, ENCSR153HNT, GSE68388, GSE50893
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Cell type: MCF-7, GM12892, H1-hESC, Fibroblast, HCT-116, Hep-G2, CVB-hiPSC, GM12878, HUES64, H9-hESC, Liver, SK-N-SH, K-562, CNCCs-H9ESC, HuCC-T1, DKO
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 11% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.822
- Subunit: SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
66% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 65%,
"7_Enh": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF394, FOXO1, MAFG, CHD8, ZNF496, MYCN, TBL1X, TOP2A, SS18, MEIS2, ZFX, MEIS1, ZBTB17, GTF2B, ZSCAN5A, SOX2, FOXA1, WT1, SMAD3, ERG3, ZNF823, XBP1, PBX2, HOXB13, TWIST1, SMARCC1, RELA, ZBTB2, NEUROD1, ATF3, NFIC, EOMES, SMARCA4, RAD21, ISL1, ARNT, OTX2, GATA3, PRDM9, SMC3, PBX3, MAX, XRCC5, TP63, NFE2, HAND2, NR2F6, MED1, CEBPB, SRSF3, KLF5, ELF1, NR2F2, ETV1, NR2F1, EZH2, ESR1, MED26, MED, EBF3, T, TCF12, CTCF, SPI1, EP300, BCL11A, AR, GATA6, GATA2, MAML3, FLI1, BRD4, TCF3, TEAD4, STAG1
- Target gene symbol (double-evidenced CRMs): MIS18A,TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops