- Basic information
- CohesinDB ID: CDBP00416869
- Locus: chr21-32232980-32234166
-
Data sourse: ENCSR000BTU, GSE152721, GSE206145-NatGen2015, GSE101921
-
Cell type: Ishikawa, HCAEC, Fibroblast, HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Mau2,Rad21,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
66% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 68%,
"14_ReprPCWk": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: FOXO1, PAX7, NANOG, MAFG, CTNNB1, FOXA2, POU5F1, NKX2-2, ZNF496, SOX2, TOP2A, ZFX, ZSCAN16, ZBTB17, ZBTB48, XBP1, MAFF, FOXA1, HOXB13, ERG, YY1, RELA, RUNX2, CHD7, GRHL3, HIF1A, RXRA, SMC3, PGR, TAL1, FOXM1, NKX3-1, MITF, VDR, TLE3, NR3C1, CEBPB, CDX2, ARNTL, SCRT2, PIAS1, EZH2, CHD8, NCOA1, C11orf30, EBF3, CTCF, JUN, MAFK, BCL11A, BAF155, EP300, SPI1, AR, GATA6, USF1, ZNF257, RXR, GATA2, EED, SCRT1, BRD4, SMC1, TEAD4, BRCA1, PDX1, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): HUNK,TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 8
- Related genes and loops
- Related gene:
ENSG00000156299,
ENSG00000142149,
- Related loop:
chr21:31250000-31275000~~chr21:32225000-32250000,
chr21:31775000-31800000~~chr21:32225000-32250000,
chr21:31800000-31825000~~chr21:32225000-32250000,
chr21:31825000-31850000~~chr21:32225000-32250000,
chr21:31950000-31975000~~chr21:32225000-32250000,
chr21:31975000-32000000~~chr21:32225000-32250000,
chr21:32025000-32050000~~chr21:32225000-32250000,
chr21:32075000-32100000~~chr21:32225000-32250000,
chr21:32125000-32150000~~chr21:32225000-32250000,