- Basic information
- CohesinDB ID: CDBP00416870
- Locus: chr21-32236079-32236414
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Data sourse: GSE206145, GSE206145-NatGen2015
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Cell type: RPE, Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
66% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 75%,
"14_ReprPCWk": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RELA, MED1, NR3C1, CEBPB, POU2F2, MYCN, ZFX, EZH2, GRHL3, ESR1, XBP1, WT1, CTCF, SRF, MAZ, APC, ZIM3, TP63, PRDM10
- Target gene symbol (double-evidenced CRMs): HUNK,TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops
- Related gene:
ENSG00000156299,
ENSG00000142149,
- Related loop:
chr21:31250000-31275000~~chr21:32225000-32250000,
chr21:31775000-31800000~~chr21:32225000-32250000,
chr21:31800000-31825000~~chr21:32225000-32250000,
chr21:31825000-31850000~~chr21:32225000-32250000,
chr21:31950000-31975000~~chr21:32225000-32250000,
chr21:31975000-32000000~~chr21:32225000-32250000,
chr21:32025000-32050000~~chr21:32225000-32250000,
chr21:32075000-32100000~~chr21:32225000-32250000,
chr21:32125000-32150000~~chr21:32225000-32250000,
chr21:32135152-32137406~~chr21:32240370-32241826,