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Basic information

CohesinDB ID: CDBP00416878

Locus: chr21-32250431-32250902

Data sourse: GSE116344, GSE67783, ENCSR153HNT

Cell type: K-562, RH4, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 90% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 43%, "14_ReprPCWk": 35%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, XBP1, FOXA1, SUZ12, PBX2, CHD7, CBFB, ZNF736, JMJD1C, MYOG, ETV1, RBM39, ESR1, OCA2, CTCF, TCF12, BAF155, TRIM24, ZNF528, SMC1, TEAD4, KMT2B, PDX1, RBPJ, TFAP2C, CHD8, BRD1, ZSCAN5D, MYCN, POU5F1, TOP2A, DUX4, ZSCAN5A, STAT1, ERG, ASCL1, ZBTB8A, ETS1, EZH1, RAD21, GRHL3, NKX3-1, RCOR1, VDR, CEBPB, CREB1, EZH2, GABPB1, SPI1, ZNF664, HDAC2, GATA2, SIX2, FLI1, RUNX1, CEBPA, EZH2phosphoT487, NKX2-2, SIN3A, ZFX, ZNF534, ERG3, SMARCC1, CREBBP, ARNT, CDK8, MED1, MYB, PIAS1, ZMYM3, USF1, REST, RBM25, STAG1, ZNF283, CBFA2T2, FOXA2, WT1, FOXF1, HOXB13, KDM1A, YY1, RELA, SP140, HIF1A, OTX2, GATA3, ZNF519, TAL1, MAX, ZNF143, CBX2, NCOA3, TP53, ZNF334, MYOD1, PAX3-FOXO1, AR, TAF1, EGR1, RNF2, BRD4, MAZ

Target gene symbol (double-evidenced CRMs): CFAP298-TCP10L,HUNK,TIAM1,SCAF4

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000156299, ENSG00000156304, ENSG00000142149, ENSG00000265590,

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Deatailed information for cohesin site CDBP00416878