- Basic information
- CohesinDB ID: CDBP00416880
- Locus: chr21-32252822-32254394
-
Data sourse: ENCSR000BLD, ENCSR000EFJ, ENCSR230ZWH, GSE86191, ENCSR000BLY, ENCSR000EHW, GSE206145-NatGen2015, GSE206145, ENCSR000EHX, ENCSR153HNT, GSE83726, GSE116344, GSE165895
-
Cell type: RPE, H1-hESC, Fibroblast, HCT-116, RH4, IMR-90, SK-N-SH, K-562, Liver, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.889
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 35%,
"14_ReprPCWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: ZNF283, PGR, ZSCAN5D, MYCN, E2F7, TOP2A, CRY1, NME2, ZFX, XBP1, MEIS2, WT1, ZBTB48, CHD2, SIN3A, TEAD4, TET2, ZBTB33, ZSCAN5A, ZNF513, PBX2, YY1, RELA, ATF3, RUNX2, NFIC, SMARCA4, RAD21, SP140, NRF1, ISL1, TCF4, GATA3, PBX3, MAX, FOXM1, ZNF143, IKZF1, RCOR1, GATA1, HAND2, NR3C1, CEBPB, NR2F2, ETV1, EZH2, PKNOX1, PITX3, ZNF334, EBF3, CTCF, TCF12, JUN, EP300, SP1, BHLHE40, AR, TAF1, GATA2, REST, ZNF366, HSF1, JUND, CLOCK, MAZ, SMC3, FOSL2
- Target gene symbol (double-evidenced CRMs): SCAF4,TIAM1,CFAP298-TCP10L,HUNK
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 11
- Related genes and loops
- Related gene:
ENSG00000156299,
ENSG00000156304,
ENSG00000142149,
ENSG00000265590,
- Related loop:
chr21:31100000-31125000~~chr21:32250000-32275000,
chr21:31150000-31175000~~chr21:32250000-32275000,
chr21:31175000-31200000~~chr21:32250000-32275000,
chr21:31200000-31225000~~chr21:32250000-32275000,
chr21:31250000-31275000~~chr21:32225000-32250000,
chr21:31622590-31624578~~chr21:32257174-32259289,
chr21:31622890-31624815~~chr21:32257354-32259325,
chr21:31725000-31750000~~chr21:32250000-32275000,
chr21:31750000-31775000~~chr21:32250000-32275000,
chr21:31775000-31800000~~chr21:32225000-32250000,
chr21:31775000-31800000~~chr21:32250000-32275000,
chr21:31780113-31781908~~chr21:32257425-32259313,
chr21:31780114-31782449~~chr21:32257201-32259301,
chr21:31780119-31781903~~chr21:32257467-32259276,
chr21:31780122-31781850~~chr21:32257426-32259309,
chr21:31780127-31781738~~chr21:32257453-32259309,
chr21:31780134-31782078~~chr21:32256511-32259378,
chr21:31780142-31781787~~chr21:32257174-32259289,
chr21:31780142-31781815~~chr21:32257381-32259299,
chr21:31780158-31781873~~chr21:32256411-32259438,
chr21:31780165-31781913~~chr21:32257185-32259313,
chr21:31780170-31781740~~chr21:32257456-32259286,
chr21:31780176-31781715~~chr21:32257195-32260019,
chr21:31780231-31781818~~chr21:32257685-32259278,
chr21:31780232-31781825~~chr21:32257190-32259329,
chr21:31780359-31781760~~chr21:32257354-32259325,
chr21:31780368-31781705~~chr21:32257665-32259284,
chr21:31780374-31781732~~chr21:32257419-32259297,
chr21:31780426-31781750~~chr21:32257414-32259287,
chr21:31780470-31781721~~chr21:32257487-32259412,
chr21:31780493-31781691~~chr21:32257422-32259254,
chr21:31784874-31786970~~chr21:32256543-32259299,
chr21:31784900-31787437~~chr21:32256367-32259995,
chr21:31784954-31787383~~chr21:32256342-32259326,
chr21:31784991-31787044~~chr21:32257192-32259306,
chr21:31784993-31787270~~chr21:32256274-32259275,
chr21:31784999-31787233~~chr21:32256341-32259331,
chr21:31785031-31787247~~chr21:32256511-32259378,
chr21:31785034-31787230~~chr21:32256411-32259438,
chr21:31785041-31787093~~chr21:32257381-32259299,
chr21:31785050-31787026~~chr21:32257438-32259314,
chr21:31785106-31787360~~chr21:32256462-32259302,
chr21:31785152-31787114~~chr21:32257190-32259329,
chr21:31785185-31787232~~chr21:32257399-32259289,
chr21:31785196-31787413~~chr21:32257174-32259289,
chr21:31785206-31787299~~chr21:32257185-32259313,
chr21:31785212-31787770~~chr21:32257426-32259309,
chr21:31785215-31787339~~chr21:32257425-32259313,
chr21:31785218-31787331~~chr21:32256496-32259419,
chr21:31785220-31787287~~chr21:32257395-32259361,
chr21:31785240-31787470~~chr21:32257315-32259388,
chr21:31785244-31787333~~chr21:32257487-32259412,
chr21:31785247-31787088~~chr21:32257448-32259319,
chr21:31785255-31787043~~chr21:32257456-32259286,
chr21:31785255-31787126~~chr21:32256545-32259247,
chr21:31785270-31788289~~chr21:32257201-32259301,
chr21:31785274-31787238~~chr21:32257419-32259292,
chr21:31785286-31787343~~chr21:32257414-32259264,
chr21:31785300-31786985~~chr21:32257739-32259287,
chr21:31785309-31786753~~chr21:32257402-32259244,
chr21:31785324-31787086~~chr21:32256476-32259292,
chr21:31785340-31787022~~chr21:32257685-32259278,
chr21:31785342-31786777~~chr21:32257453-32259309,
chr21:31785386-31787148~~chr21:32257354-32259325,
chr21:31785419-31786802~~chr21:32257417-32259304,
chr21:31785437-31786931~~chr21:32257431-32259307,
chr21:31785448-31786701~~chr21:32257665-32259284,
chr21:31800000-31825000~~chr21:32225000-32250000,
chr21:31825000-31850000~~chr21:32225000-32250000,
chr21:31825000-31850000~~chr21:32250000-32275000,
chr21:31850000-31875000~~chr21:32250000-32275000,
chr21:31865157-31867306~~chr21:32257685-32259278,
chr21:31865168-31867682~~chr21:32256342-32259326,
chr21:31865180-31867368~~chr21:32257185-32259313,
chr21:31865190-31867889~~chr21:32256367-32259995,
chr21:31865192-31867355~~chr21:32257195-32259363,
chr21:31865195-31867134~~chr21:32257381-32259299,
chr21:31865197-31867074~~chr21:32256511-32259378,
chr21:31865202-31867213~~chr21:32257174-32259289,
chr21:31865202-31867229~~chr21:32257395-32259361,
chr21:31865206-31867094~~chr21:32256476-32259292,
chr21:31865207-31867006~~chr21:32256496-32259419,
chr21:31865209-31867146~~chr21:32257476-32259450,
chr21:31865210-31867077~~chr21:32257453-32259309,
chr21:31865211-31867117~~chr21:32257438-32259314,
chr21:31865214-31867338~~chr21:32257201-32259301,
chr21:31865217-31867110~~chr21:32257228-32259294,
chr21:31865220-31867254~~chr21:32256411-32259438,
chr21:31865221-31867042~~chr21:32257414-32259264,
chr21:31865221-31867070~~chr21:32257315-32259388,
chr21:31865222-31867020~~chr21:32257456-32259286,
chr21:31865228-31867355~~chr21:32257190-32259329,
chr21:31865230-31867361~~chr21:32256274-32259275,
chr21:31865232-31867115~~chr21:32257195-32260019,
chr21:31865233-31867108~~chr21:32257487-32259412,
chr21:31865235-31867832~~chr21:32257485-32259289,
chr21:31865244-31867006~~chr21:32257426-32259309,
chr21:31865247-31867652~~chr21:32257419-32259292,
chr21:31865248-31867144~~chr21:32256462-32259302,
chr21:31865252-31867066~~chr21:32257486-32259262,
chr21:31865272-31867342~~chr21:32256341-32259331,
chr21:31865293-31867052~~chr21:32257402-32259244,
chr21:31865357-31867257~~chr21:32257638-32259280,
chr21:31865428-31867009~~chr21:32257414-32259287,
chr21:31865442-31866981~~chr21:32257354-32259325,
chr21:31865450-31867127~~chr21:32257447-32259293,
chr21:31865459-31867029~~chr21:32257757-32259222,
chr21:31865464-31867091~~chr21:32256545-32259247,
chr21:31865464-31867092~~chr21:32257192-32259306,
chr21:31865470-31866930~~chr21:32257417-32259304,
chr21:31865481-31867115~~chr21:32257677-32259293,
chr21:31865496-31866966~~chr21:32257419-32259297,
chr21:31865505-31867043~~chr21:32256543-32259299,
chr21:31865515-31867075~~chr21:32257445-32259345,
chr21:31865537-31866893~~chr21:32257665-32259284,
chr21:31865585-31866840~~chr21:32257379-32259282,
chr21:31865594-31866849~~chr21:32257485-32259262,
chr21:31871809-31875540~~chr21:32256411-32259438,
chr21:31872039-31874494~~chr21:32256511-32259378,
chr21:31872042-31874581~~chr21:32256342-32259326,
chr21:31872118-31875754~~chr21:32256367-32259995,
chr21:31872126-31874557~~chr21:32257195-32259363,
chr21:31872415-31873934~~chr21:32257185-32259313,
chr21:31872509-31873790~~chr21:32257190-32259329,
chr21:31872517-31873744~~chr21:32257476-32259450,
chr21:31875000-31900000~~chr21:32250000-32275000,
chr21:31933177-31934710~~chr21:32257228-32259294,
chr21:31933279-31934543~~chr21:32256462-32259302,
chr21:31950000-31975000~~chr21:32225000-32250000,
chr21:31950000-31975000~~chr21:32250000-32275000,
chr21:31975000-32000000~~chr21:32225000-32250000,
chr21:31975000-32000000~~chr21:32250000-32275000,
chr21:31991338-31992891~~chr21:32257485-32259289,
chr21:31991347-31993191~~chr21:32257436-32259286,
chr21:31991417-31992782~~chr21:32257395-32259361,
chr21:31991454-31992738~~chr21:32257485-32259262,
chr21:31991470-31992926~~chr21:32257476-32259450,
chr21:31991525-31992800~~chr21:32256274-32259275,
chr21:32000000-32025000~~chr21:32250000-32275000,
chr21:32025000-32050000~~chr21:32225000-32250000,
chr21:32050000-32075000~~chr21:32250000-32275000,
chr21:32075000-32100000~~chr21:32225000-32250000,
chr21:32075000-32100000~~chr21:32250000-32275000,
chr21:32095899-32097665~~chr21:32256342-32259326,
chr21:32095914-32097481~~chr21:32256462-32259302,
chr21:32095923-32097744~~chr21:32257185-32259313,
chr21:32095946-32097766~~chr21:32256274-32259275,
chr21:32095947-32097429~~chr21:32257192-32259306,
chr21:32095949-32097315~~chr21:32257417-32259304,
chr21:32095949-32097664~~chr21:32256341-32259331,
chr21:32095950-32097502~~chr21:32257195-32259363,
chr21:32095978-32097865~~chr21:32256367-32259995,
chr21:32095998-32097302~~chr21:32257467-32259276,
chr21:32096061-32097312~~chr21:32257419-32259297,
chr21:32100000-32125000~~chr21:32250000-32275000,
chr21:32125000-32150000~~chr21:32225000-32250000,
chr21:32125000-32150000~~chr21:32250000-32275000,
chr21:32134808-32137469~~chr21:32257190-32259329,
chr21:32135152-32137406~~chr21:32257185-32259313,
chr21:32250000-32275000~~chr21:32550000-32575000,