Deatailed information for cohesin site CDBP00416898

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  • Basic information
  • CohesinDB ID: CDBP00416898
  • Locus: chr21-32305776-32306803
  • Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE72082, GSE116868, GSE105028, GSE131606, GSE108869, GSE25021, ENCSR917QNE, GSE67783, ENCSR000BKV, GSE86191, GSE138405, GSE76893, GSE101921, GSE152721, GSE206145-NatGen2015, GSE116344, GSE106870, GSE145327, GSE94872, ENCSR000EEG, ENCSR000BLS, GSE206145, ENCSR000ECE, GSE97394, ENCSR167MTG, GSE110061, GSE129526, ENCSR153HNT, GSE83726, GSE50893
  • Cell type: RH4, CVB-hiPSC, CVI-hiPSC, Liver, H9-hESC, RPE, Fibroblast, HeLa-S3, K-562, DKO, GM18526, H1-hESC, MB157, CNCCs-H9ESC, HAP1, HUES64, MCF-7, Hela-Kyoto, HCT-116, Hep-G2, HUVEC, HCAEC, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 11% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.744
  • Subunit: SA1,Rad21,SMC1,SA2,SMC3
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: TSS,TES
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: non-Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 90% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): False
  • Chromatin annotation: "5_TxWk": 50%, "4_Tx": 16%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: HMG20A, SOX2, XBP1, FOXA1, HLF, LEO1, HDGF, ATF3, ZNF362, CTCFL, CHD7, ZBTB44, ZNF189, MECOM, MITF, TEAD1, ZNF121, RBM39, SNAI2, RCOR2, ESR1, CTCF, TCF12, EP300, GATA6, SOX5, RYBP, E2F1, ZNF528, SMC1, TEAD4, FOXA3, GATAD2A, TFAP2C, EED, GLIS1, POU2F2, CHD8, BRD1, ZNF263, POU5F1, RUNX1T1, MYCN, ZBTB17, ZBTB48, ZSCAN5A, SRF, DDX5, SAP130, ERG, ETS1, EZH1, HOMEZ, RAD21, FOXP2, GRHL3, XRCC5, PRDM14, NFE2, NR2F6, NR3C1, CEBPB, CREB1, CCAR2, ZHX2, ZNF664, MIXL1, ZNF257, HDAC2, ZNF644, MXD3, ZNF146, FLI1, ZGPAT, RUNX1, SMC1A, BCL6, CEBPA, SOX13, ZFX, SMAD3, TET2, ERG3, ZNF770, SMARCC1, NSD2, PRDM10, ZBTB2, ZNF384, PRPF4, RARA, TAF15, ARNT, ATF2, SMAD4, ZEB2, SUPT5H, CHD1, TEAD3, CEBPD, ZMYM3, SMAD1, ZNF3, C11orf30, RBM22, GSPT2, ZBTB7A, ZNF479, RBM25, ASH2L, CTBP2, BCOR, FOXP1, SMC3, STAG1, TBL1X, FOXA2, RBBP5, PAF1, WT1, ZNF574, ZBTB33, MEF2C, ZNF580, HOXB13, KDM1A, YY1, RELA, NEUROD1, SP140, ZIC2, HIF1A, PCGF1, OTX2, TAL1, MAX, ZNF143, AGO2, PLAG1, CEBPG, NR2F1, TP53, ZNF334, ARID4B, AR, TAF1, HSF1, MYNN, NOTCH3, BRD4, CLOCK, MAZ, AHR, FOSL2
  • Target gene symbol (double-evidenced CRMs): PAXBP1,URB1,EVA1C,CFAP298-TCP10L,SYNJ1,CFAP298
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 117
  • Number of somatic mutations (non-coding): 39
  • Related genes and loops
  • Related gene: ENSG00000142207, ENSG00000166979, ENSG00000265590, ENSG00000159079, ENSG00000159082, ENSG00000159086,
  • Related loop: chr21:29050000-29075000~~chr21:32300000-32325000, chr21:32300000-32325000~~chr21:32450000-32475000, chr21:32300000-32325000~~chr21:32575000-32600000, chr21:32300000-32325000~~chr21:32600000-32625000, chr21:32300000-32325000~~chr21:32725000-32750000, chr21:32305431-32307333~~chr21:32600164-32601910,
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