- Basic information
- CohesinDB ID: CDBP00416899
- Locus: chr21-32307314-32307797
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Data sourse: GSE67783, GSE86191
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Cell type: HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 72%,
"4_Tx": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: HMG20A, SOX2, XBP1, FOXA1, HLF, LEO1, HDGF, ATF3, ZNF362, CTCFL, CHD7, ZBTB44, ZNF189, MECOM, MITF, TEAD1, ZNF121, RBM39, SNAI2, RCOR2, ESR1, CTCF, TCF12, EP300, GATA6, SOX5, RYBP, E2F1, ZNF528, SMC1, TEAD4, FOXA3, GATAD2A, TFAP2C, EED, GLIS1, POU2F2, CHD8, BRD1, ZNF263, POU5F1, RUNX1T1, MYCN, ZBTB17, ZBTB48, ZSCAN5A, SRF, DDX5, SAP130, ERG, ETS1, EZH1, HOMEZ, RAD21, FOXP2, GRHL3, XRCC5, PRDM14, NFE2, NR2F6, NR3C1, CEBPB, CREB1, CCAR2, ZHX2, ZNF664, MIXL1, ZNF257, HDAC2, ZNF644, MXD3, ZNF146, FLI1, ZGPAT, RUNX1, SMC1A, BCL6, CEBPA, SOX13, ZFX, SMAD3, TET2, ERG3, ZNF770, SMARCC1, NSD2, PRDM10, ZBTB2, ZNF384, PRPF4, RARA, TAF15, ARNT, ATF2, SMAD4, ZEB2, SUPT5H, CHD1, TEAD3, CEBPD, ZMYM3, SMAD1, ZNF3, C11orf30, RBM22, GSPT2, ZBTB7A, ZNF479, RBM25, ASH2L, CTBP2, BCOR, FOXP1, SMC3, STAG1, TBL1X, FOXA2, RBBP5, PAF1, WT1, ZNF574, ZBTB33, MEF2C, ZNF580, HOXB13, KDM1A, YY1, RELA, NEUROD1, SP140, ZIC2, HIF1A, PCGF1, OTX2, TAL1, MAX, ZNF143, AGO2, PLAG1, CEBPG, NR2F1, TP53, ZNF334, ARID4B, AR, TAF1, HSF1, MYNN, NOTCH3, BRD4, CLOCK, MAZ, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): EVA1C,SYNJ1,CFAP298,CFAP298-TCP10L,PAXBP1,URB1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 6
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000142207,
ENSG00000166979,
ENSG00000265590,
ENSG00000159079,
ENSG00000159082,
ENSG00000159086,
- Related loop:
chr21:29050000-29075000~~chr21:32300000-32325000,
chr21:32300000-32325000~~chr21:32450000-32475000,
chr21:32300000-32325000~~chr21:32575000-32600000,
chr21:32300000-32325000~~chr21:32600000-32625000,
chr21:32300000-32325000~~chr21:32725000-32750000,
chr21:32305431-32307333~~chr21:32600164-32601910,