- Basic information
- CohesinDB ID: CDBP00416900
- Locus: chr21-32308617-32310741
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Data sourse: GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 61%,
"4_Tx": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, GLIS1, TRP47, POU2F2, BRD1, ZSCAN5D, MYCN, ZNF263, AGO1, PAF1, ZFX, FOXA2, XBP1, PPARG, ZBTB48, WT1, ZSCAN5A, DUX4, FOXA1, TET2, ERG3, LEO1, ZFHX2, KDM1A, ERG, RELA, ZNF384, ATF3, AHR, MYC, SP140, GRHL3, HIF1A, ARNT, NKX2-1, ATF2, SMC3, GLYR1, GABPA, SUPT5H, AGO2, SNRNP70, DNMT3B, PRDM14, PLAG1, VDR, CEBPB, TEAD3, ELF1, TEAD1, NR2F1, ESR1, GRHL2, EGR2, CTCF, RBM22, SPI1, AR, POU2F3, ZBTB26, JUND, MAZ, AATF, TEAD4, ZNF175, STAG1, TFAP2C, EED
- Target gene symbol (double-evidenced CRMs): SYNJ1,CFAP298-TCP10L,CFAP298,URB1,PAXBP1,EVA1C
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 36
- Number of somatic mutations (non-coding): 12
- Related genes and loops
- Related gene:
ENSG00000142207,
ENSG00000166979,
ENSG00000265590,
ENSG00000159079,
ENSG00000159082,
ENSG00000159086,
- Related loop:
chr21:29050000-29075000~~chr21:32300000-32325000,
chr21:32300000-32325000~~chr21:32450000-32475000,
chr21:32300000-32325000~~chr21:32575000-32600000,
chr21:32300000-32325000~~chr21:32600000-32625000,
chr21:32300000-32325000~~chr21:32725000-32750000,
chr21:32305431-32307333~~chr21:32600164-32601910,