- Basic information
- CohesinDB ID: CDBP00416908
- Locus: chr21-32319827-32320459
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Data sourse: GSE67783, GSE86191, ENCSR404BPV, ENCSR198ZYJ, ENCSR153HNT
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Cell type: K-562, Neurons-H1, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"4_Tx": 79%,
"5_TxWk": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, SOX2, XBP1, FOXA1, LEO1, HNRNPUL1, CHD7, MORC2, CBFB, GLYR1, TP63, ZNF736, TEAD1, RBM39, SNAI2, SMAD5, ESR1, OCA2, CTCF, EP300, BAF155, MNT, LMO1, PAX8, TEAD4, GATAD2A, RBPJ, GLIS1, ZSCAN5D, MYCN, POU5F1, ZNF263, TOP2A, ZMYND11, ZBTB48, ZSCAN5A, STAT1, DUX4, ERG2, ERG, OGG1, ETS1, MYC, SMARCA4, GRHL3, PROX1, STAT3, ZNF614, DNMT3B, NR2F6, NR3C1, CEBPB, SRSF3, JMJD6, GABPB1, SPI1, SSRP1, GATA2, MXD3, FLI1, HCFC1R1, RUNX1, SMC1A, SIRT6, ZFX, POU4F2, TET2, ERG3, RUNX2, SMAD2, CDK6, ARNT, ZNF48, PRDM9, SMAD4, PBX3, SUPT5H, SNRNP70, TEAD3, ZEB1, KDM6B, MYB, SCRT2, KLF9, SREBF2, RBM22, BCL11A, HNF4A, REST, TCF3, FOXP1, AATF, SMC3, STAG1, TRP47, ZNF283, AGO1, FOXA2, TBL1X, NFATC1, PAF1, ZNF600, GTF2B, WT1, ESR2, CDK9, HOXB13, BCL3, ZKSCAN1, KDM1A, YY1, RELA, NEUROD1, SP140, ZIC2, BATF, TAL1, MAX, NRIP1, ZNF143, AGO2, KLF4, NCOA3, NR2F1, NEUROG2, KDM5B, ZNF334, MYOD1, EGR2, AR, RXR, ZBTB42, HEXIM1, HSF1, ZBTB26, BRD4, JUND, SCRT1, MAZ, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): EVA1C,SYNJ1,CFAP298-TCP10L,URB1,CFAP298,PAXBP1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 1
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000142207,
ENSG00000166979,
ENSG00000265590,
ENSG00000159079,
ENSG00000159082,
ENSG00000159086,
- Related loop:
chr21:29025000-29050000~~chr21:32325000-32350000,
chr21:29050000-29075000~~chr21:32300000-32325000,
chr21:29050000-29075000~~chr21:32325000-32350000,
chr21:32300000-32325000~~chr21:32450000-32475000,
chr21:32300000-32325000~~chr21:32575000-32600000,
chr21:32300000-32325000~~chr21:32600000-32625000,
chr21:32300000-32325000~~chr21:32725000-32750000,
chr21:32325000-32350000~~chr21:32750000-32775000,
chr21:32325000-32350000~~chr21:33500000-33525000,
chr21:32325000-32350000~~chr21:33525000-33550000,