Deatailed information for cohesin site CDBP00416913

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  • Basic information
  • CohesinDB ID: CDBP00416913
  • Locus: chr21-32328118-32330129
  • Data sourse: ENCSR230ZWH, GSE132649, GSE101921, GSE206145-NatGen2015, ENCSR917QNE
  • Cell type: T-47D, Liver, Fibroblast, HCAEC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 3% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.956
  • Subunit: SA1,Rad21,SMC1,SA2,Mau2
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 90% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "5_TxWk": 38%, "4_Tx": 31%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: NFIA, CBX5, HMG20A, LCORL, SOX2, MEIS2, HNF1A, FOXA1, RBFOX2, PBX2, RXRB, LEO1, TFAP4, HDGF, ATF3, NFIC, ZFP64, ZNF362, CHD7, RUNX3, MXD4, GLYR1, ZNF736, JMJD1C, TEAD1, ELF1, TRIM28, ETV1, RCOR2, ESR1, FUS, CTCF, JUN, EP300, GATA6, SOX5, TEAD4, FOXA3, ZNF175, ZNF92, GATAD2A, PDX1, RBPJ, MLX, GLIS1, NANOG, CHD8, BRD1, POU2F2, MYCN, POU5F1, ZBTB48, ZSCAN5A, GATAD1, SAP130, NBN, ARID3A, HNF4G, ERG, ETS1, MYC, SMARCA4, EOMES, ARID1B, RAD21, HOMEZ, RXRA, NKX2-1, PROX1, MCRS1, GABPA, STAT3, ZNF614, SOX10, XRCC5, MIER3, INO80, NR2F6, VDR, NR3C1, CEBPB, CREB1, CCAR2, EZH2, ZNF652, GABPB1, SPI1, TFE3, MIXL1, HDAC2, GATA2, ZNF182, ZNF644, MXD3, FLI1, DRAP1, MXI1, ZGPAT, ZNF490, RELB, MRTFB, NFIL3, ETV5, RUNX1, THAP11, SMC1A, BCL6, CEBPA, NKX2-2, SIRT6, EZH2phosphoT487, SOX13, ZFX, FIP1L1, SMAD3, ZNF770, SP5, TRIM22, SMARCC1, MEF2A, MYBL2, RARA, ZNF384, ZNF35, RUNX2, GATA4, ARNT, HMGB2, ATF2, SMAD4, ZNF48, ZNF354A, PBX3, FOS, CDK8, SMARCB1, HMGXB4, SUPT5H, MED1, TEAD3, U2AF1, ZNF3, STAT5A, RBM22, SP1, HNF4A, IKZF5, ATF7, ASH2L, AFF1, FOXP1, SMC3, STAG1, ETV4, SKI, ZNF283, PPARG, FOXA2, CREM, MEIS1, PAF1, MIER2, GTF2B, WT1, TCF7, ZNF580, KDM1A, YY1, RELA, TARDBP, NEUROD1, JUNB, AHR, SP140, ZIC2, HIF1A, OTX2, GATA3, TAL1, MAX, GATA1, ZNF143, CEBPG, NR2F2, NEUROG2, TCF7L2, ZNF334, MYOD1, ELF3, PHF5A, KAT8, T, BHLHE40, AR, ARID4B, NFKBIZ, ZBTB26, HSF1, NOTCH3, JUND, BRD4, IKZF2, CUX1, MAZ, ZZZ3, DMAP1, FOSL2
  • Target gene symbol (double-evidenced CRMs): PAXBP1,GART,URB1,SON
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 6
  • Number of somatic mutations (non-coding): 6
  • Related genes and loops
  • Related gene: ENSG00000142207, ENSG00000159086, ENSG00000159131, ENSG00000159140,
  • Related loop: chr21:29025000-29050000~~chr21:32325000-32350000, chr21:29050000-29075000~~chr21:32300000-32325000, chr21:29050000-29075000~~chr21:32325000-32350000, chr21:31784993-31787270~~chr21:32327704-32330556, chr21:32300000-32325000~~chr21:32450000-32475000, chr21:32300000-32325000~~chr21:32575000-32600000, chr21:32300000-32325000~~chr21:32600000-32625000, chr21:32300000-32325000~~chr21:32725000-32750000, chr21:32325000-32350000~~chr21:32750000-32775000, chr21:32325000-32350000~~chr21:33500000-33525000, chr21:32325000-32350000~~chr21:33525000-33550000,
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