Deatailed information for cohesin site CDBP00416916

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  • Basic information
  • CohesinDB ID: CDBP00416916
  • Locus: chr21-32334113-32336149
  • Data sourse: ENCSR000BLD, GSE67783, GSE86191, GSE206145-NatGen2015, ENCSR153HNT, GSE165895
  • Cell type: H1-hESC, Fibroblast, HCT-116, K-562, HSPC, HFFc6
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 3% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.933
  • Subunit: SA1,Rad21,SMC1,SA2,Mau2
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 90% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "4_Tx": 54%, "6_EnhG": 15%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOSL1, XBP1, FOXA1, LEO1, MLL4, ATF3, NFIC, CHD7, CBFB, GLYR1, MITF, CDX2, ZNF629, ELF1, TEAD1, RBM39, SAP30, ESR1, OCA2, LMO2, CTCF, TCF12, JUN, EP300, KLF1, SOX4, E2F1, TEAD4, TFAP2C, RBPJ, GLIS1, POU2F2, CHD8, BRD1, POU5F1, MYCN, ZNF263, CDK7, BRD3, TOP2A, ZMYND11, ZBTB48, ZSCAN5A, DUX4, SRF, ERG2, ERG, HOXC5, OGG1, ETS1, MYC, SMARCA4, RAD21, FOXP2, GRHL3, STAT3, XRCC5, NKX3-1, RCOR1, DNMT3B, HNRNPH1, ARNTL, ZNF750, ESRRA, NR3C1, CREB1, GABPB1, ZHX2, SPI1, EHF, IRF1, KLF17, SIX2, FLI1, MXI1, NCOA2, ETV5, RUNX1, EZH2phosphoT487, NKX2-2, SIN3A, ZFX, SMAD3, TET2, NMYC, ERG3, TWIST1, RARA, ZNF384, CREBBP, RUNX2, OSR2, ZNF184, PBX4, ARNT, DAXX, NRF1, ZNF48, PBX3, SP2, SUPT5H, CHD1, FOS, SMARCB1, CDK8, MED1, ZEB1, ZNF3, RBM22, USF1, SP1, TFAP2A, ASH2L, AATF, SMC3, STAG1, TRP47, CBFA2T2, FOXA2, CBX3, PAF1, ZNF600, WT1, ESR2, KDM1A, YY1, RELA, NEUROD1, JUNB, SP140, ZIC2, TCF4, HIF1A, OTX2, GATA3, TAL1, MAX, NRIP1, ZNF143, AGO2, HAND2, KLF4, NCOA3, NR2F2, NEUROG2, NR2F1, KDM5B, TCF7L2, TP53, ZNF334, NFKB1, MYOD1, T, BRD2, ELF3, AR, ZNF579, RXR, EGLN2, ZBTB42, HSF1, RNF2, BRD4, JUND, CLOCK, MAZ, AHR, FOSL2
  • Target gene symbol (double-evidenced CRMs): PAXBP1,SON,URB1,GART
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 27
  • Number of somatic mutations (non-coding): 16
  • Related genes and loops
  • Related gene: ENSG00000142207, ENSG00000159086, ENSG00000159131, ENSG00000159140,
  • Related loop: chr21:29025000-29050000~~chr21:32325000-32350000, chr21:29050000-29075000~~chr21:32325000-32350000, chr21:31784993-31787270~~chr21:32327704-32330556, chr21:32325000-32350000~~chr21:32750000-32775000, chr21:32325000-32350000~~chr21:33500000-33525000, chr21:32325000-32350000~~chr21:33525000-33550000,
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