- Basic information
- CohesinDB ID: CDBP00416924
- Locus: chr21-32352521-32353449
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Data sourse: GSE86191, GSE67783, GSE83726
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Cell type: RH4, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"4_Tx": 88%,
"5_TxWk": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, XBP1, FOXA1, RBFOX2, LEO1, ATF3, THAP1, RUNX3, WDHD1, CBFB, GLYR1, SMARCE1, PAX5, TP63, MITF, JMJD1C, ELF1, TRIM28, TEAD1, RBM39, ETV1, ZNF217, ESR1, LMO2, COBLL1, JUN, CTCF, BAF155, E4F1, EP300, MNT, DPF2, SOX4, TRIM24, RFX5, E2F1, ZNF280A, TEAD4, TFAP2C, EED, GLIS1, JARID2, POU2F2, CHD8, ZSCAN5D, POU5F1, MYCN, TOP2A, RUNX1T1, CTBP1, ZBTB48, ZSCAN5A, DDX5, ERG, OGG1, NFKB2, ETS1, MYC, SMARCA4, GRHL3, NKX2-1, GABPA, STAT3, XRCC5, NKX3-1, RCOR1, DNMT3B, HNRNPH1, NR3C1, ESRRA, CEBPB, ZNF750, CREB1, EZH2, GRHL2, EBF3, GABPB1, ZHX2, SPI1, HDAC2, GATA2, FLI1, SREBF1, RELB, NCOA2, PTBP1, RUNX1, CBX1, SMC1A, CEBPA, SIRT6, SIN3A, ZFX, SMAD3, TET2, TWIST1, ZXDC, CREBBP, ZNF384, RUNX2, GR, ARNT, PBX4, NRF1, ZNF48, PRDM9, FOXM1, SUPT5H, CHD1, FOS, SMARCB1, ZEB1, SCRT2, PIAS1, KLF9, SETDB1, ZNF22, RBM22, BCL11A, TFAP2A, HNF4A, REST, ZNF479, POU2F3, ASH2L, AFF1, FOXP1, AATF, SMC3, STAG1, TRP47, ZNF316, CBX3, AGO1, FOXA2, TBL1X, PAF1, EBF1, PPARG, ZNF692, WT1, ESR2, HOXB13, KDM1A, YY1, RELA, NEUROD1, ISL1, SP140, ZIC2, SKIL, HIF1A, OTX2, GATA3, BATF, TAL1, MAX, NRIP1, ZNF143, AGO2, MTA1, HAND2, CBX2, CEBPG, KLF4, NCOA3, NR2F2, NR2F1, NEUROG2, KDM5B, TP53, ZNF334, NFKB1, MYOD1, PHOX2B, AR, ZBTB40, RXR, EGLN2, ZBTB42, HEXIM1, EGR1, HSF1, ZBTB26, SCRT1, BRD4, CLOCK, MAZ, ZZZ3, ZNF24, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): CFAP298,GART,CFAP298-TCP10L,SYNJ1,URB1,PAXBP1,SON
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 12
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000142207,
ENSG00000265590,
ENSG00000159079,
ENSG00000159082,
ENSG00000159086,
ENSG00000159131,
ENSG00000159140,
- Related loop:
chr21:27500000-27525000~~chr21:32350000-32375000,
chr21:29025000-29050000~~chr21:32325000-32350000,
chr21:29050000-29075000~~chr21:32325000-32350000,
chr21:29050000-29075000~~chr21:32350000-32375000,
chr21:32325000-32350000~~chr21:32750000-32775000,
chr21:32325000-32350000~~chr21:33500000-33525000,
chr21:32325000-32350000~~chr21:33525000-33550000,
chr21:32350000-32375000~~chr21:32600000-32625000,
chr21:32350000-32375000~~chr21:32725000-32750000,
chr21:32350000-32375000~~chr21:32750000-32775000,
chr21:32350000-32375000~~chr21:33525000-33550000,
chr21:32350000-32375000~~chr21:34325000-34350000,