- Basic information
- CohesinDB ID: CDBP00416928
- Locus: chr21-32358689-32359007
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Data sourse: GSE67783, GSE86191
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Cell type: HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"4_Tx": 94%,
"5_TxWk": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, XBP1, FOXA1, SUZ12, LEO1, TFAP4, THRB, GLYR1, MXD4, TP63, MITF, JMJD1C, ETV1, ESR1, TP73, USF2, JUN, CTCF, BAF155, MNT, SOX5, IRF4, SMC1, PDX1, RBPJ, ZSCAN5D, ZNF263, MYCN, TOP2A, ID3, DUX4, ZSCAN5A, ZBTB48, SRF, SAP130, DDX5, TBP, ETS1, MYC, SMARCA4, HOMEZ, RAD21, NKX2-1, GABPA, STAT3, XRCC5, NKX3-1, PRDM14, DNMT3B, NR2F6, NR3C1, SRSF3, CREB1, GRHL2, SPI1, TFE3, GATA2, DRAP1, ETV5, RUNX1, BCL6, SMC1A, CEBPA, NKX2-2, SIN3A, ZFX, SOX13, AFF4, SMAD3, PRDM10, CREBBP, ZBTB2, NOTCH1, ARNT, NRF1, ZNF48, SMAD4, SUPT5H, HMGXB4, SNRNP70, CHD1, FOS, MED1, TEAD3, U2AF1, SMAD1, ZNF3, SREBF2, RBM22, USF1, BCL11A, REST, TCF3, SMC3, STAG1, TBL1X, FOXA2, PAF1, MIER2, WT1, CDK9, HOXB13, RELA, SP140, HIF1A, ZNF519, TAL1, MAX, NRIP1, ZNF143, MTA1, KLF4, CEBPG, NR2F2, KDM5B, TP53, ARID4B, AR, EGLN2, ZNF366, HSF1, ZBTB26, BRD4, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): PAXBP1,SON,CFAP298,GART,SYNJ1,URB1,CFAP298-TCP10L
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000142207,
ENSG00000265590,
ENSG00000159079,
ENSG00000159082,
ENSG00000159086,
ENSG00000159131,
ENSG00000159140,
- Related loop:
chr21:27500000-27525000~~chr21:32350000-32375000,
chr21:29050000-29075000~~chr21:32350000-32375000,
chr21:32350000-32375000~~chr21:32600000-32625000,
chr21:32350000-32375000~~chr21:32725000-32750000,
chr21:32350000-32375000~~chr21:32750000-32775000,
chr21:32350000-32375000~~chr21:33525000-33550000,
chr21:32350000-32375000~~chr21:34325000-34350000,
chr21:32359189-32360657~~chr21:32599840-32601900,