Deatailed information for cohesin site CDBP00416929

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  • Basic information
  • CohesinDB ID: CDBP00416929
  • Locus: chr21-32359599-32360314
  • Data sourse: ENCSR000BLD, GSE104888, ENCSR230ZWH, GSE72082, ENCSR000BSB, ENCSR501LQA, GSE116868, ENCSR000BLY, GSE121355, GSE111537, GSE131606, GSE108869, ENCSR000EDW, GSE25021, ENCSR000BUC, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE93080, GSE67783, ENCSR000BKV, GSE86191, GSE138405, GSE76893, GSE101921, GSE206145-NatGen2015, GSE138105, ENCSR703TNG, GSE116344, ENCSR000EEG, ENCSR338DUC, ENCSR193NSH, ENCSR000BLS, GSE206145, ENCSR000ECE, ENCSR247LSH, ENCSR807WAC, ENCSR620NWG, ENCSR748MVX, ENCSR767DFK, ENCSR981FDC, ENCSR217ELF, ENCSR000BTQ, GSE105004, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, GSE110061, GSE129526, GSE111913, ENCSR335RKQ, ENCSR054FKH, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE83726, GSE126990, GSE50893, ENCSR000ECS, GSE38411
  • Cell type: RH4, GM2610, SLK, GM19240, Liver, HuCC-T1, RPE, GM2630, Fibroblast, Ishikawa, HeLa-S3, IMR-90, BCBL-1, K-562, DKO, H1-hESC, SNYDER, MB157, GM12878, GM12891, SK-N-SH, GM19239, RT-112, MCF-7, GM12892, Hela-Kyoto, HCT-116, Hep-G2, A-549, HCAEC, GM19238, HeLa, OCI-AML-3, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 25% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.622
  • Subunit: SA1,Rad21,SMC1,SA2,SMC3
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 90% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "4_Tx": 84%, "5_TxWk": 9%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, PGR, XBP1, FOXA1, SUZ12, LEO1, TFAP4, THRB, GLYR1, MXD4, TP63, MITF, JMJD1C, ETV1, ESR1, TP73, USF2, JUN, CTCF, BAF155, MNT, SOX5, IRF4, SMC1, PDX1, RBPJ, ZSCAN5D, ZNF263, MYCN, TOP2A, ID3, DUX4, ZSCAN5A, ZBTB48, SRF, SAP130, DDX5, TBP, ETS1, MYC, SMARCA4, HOMEZ, RAD21, NKX2-1, GABPA, STAT3, XRCC5, NKX3-1, PRDM14, DNMT3B, NR2F6, NR3C1, SRSF3, CREB1, GRHL2, SPI1, TFE3, GATA2, DRAP1, ETV5, RUNX1, BCL6, SMC1A, CEBPA, NKX2-2, SIN3A, ZFX, SOX13, AFF4, SMAD3, PRDM10, CREBBP, ZBTB2, NOTCH1, ARNT, NRF1, ZNF48, SMAD4, SUPT5H, HMGXB4, SNRNP70, CHD1, FOS, MED1, TEAD3, U2AF1, SMAD1, ZNF3, SREBF2, RBM22, USF1, BCL11A, REST, TCF3, SMC3, STAG1, TBL1X, FOXA2, PAF1, MIER2, WT1, CDK9, HOXB13, RELA, SP140, HIF1A, ZNF519, TAL1, MAX, NRIP1, ZNF143, MTA1, KLF4, CEBPG, NR2F2, KDM5B, TP53, ARID4B, AR, EGLN2, ZNF366, HSF1, ZBTB26, BRD4, MAZ, AHR
  • Target gene symbol (double-evidenced CRMs): URB1,SON,GART,PAXBP1,SYNJ1,CFAP298,CFAP298-TCP10L
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 20
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops
  • Related gene: ENSG00000142207, ENSG00000265590, ENSG00000159079, ENSG00000159082, ENSG00000159086, ENSG00000159131, ENSG00000159140,
  • Related loop: chr21:27500000-27525000~~chr21:32350000-32375000, chr21:29050000-29075000~~chr21:32350000-32375000, chr21:32350000-32375000~~chr21:32600000-32625000, chr21:32350000-32375000~~chr21:32725000-32750000, chr21:32350000-32375000~~chr21:32750000-32775000, chr21:32350000-32375000~~chr21:33525000-33550000, chr21:32350000-32375000~~chr21:34325000-34350000, chr21:32359189-32360657~~chr21:32599840-32601900,
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