Deatailed information for cohesin site CDBP00416933

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  • Basic information
  • CohesinDB ID: CDBP00416933
  • Locus: chr21-32365681-32366109
  • Data sourse: GSE67783, ENCSR153HNT, GSE86191
  • Cell type: K-562, HCT-116, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 1% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.967
  • Subunit: SA1,Rad21
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 90% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "4_Tx": 74%, "5_TxWk": 15%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, NFIA, PGR, HMG20A, SOX2, NME2, FOXA1, RXRB, LEO1, PBX2, TFAP4, ATF3, NFIC, THRB, ZFP64, GLYR1, MECOM, TP63, JMJD1C, TEAD1, ZNF121, ELF1, ETV1, RBM39, RCOR2, ESR1, OCA2, ZNF217, CTCF, EP300, BAF155, LMO1, SOX5, PRDM4, ZNF677, FOXA3, KMT2B, GATAD2A, TFAP2C, RBPJ, MLX, POU2F2, CHD8, BRD1, MYCN, POU5F1, TOP2A, ZNF263, ZBTB48, ZSCAN5A, SRF, GATAD1, SAP130, DDX5, HNF4G, ERG, ETS1, MYC, SMARCA4, HOMEZ, RAD21, FOXP2, TOP1, RXRA, GABPA, STAT3, XRCC5, ZNF614, DNMT3B, NR2F6, HNRNPH1, ZNF750, CEBPB, SRSF3, ESRRA, NR3C1, CREB1, EZH2, BMPR1A, GRHL2, FEZF1, SPI1, TFE3, HDAC2, GATA2, ZNF644, MXD3, SIX2, FLI1, DRAP1, ZGPAT, NFIL3, NCOA2, ETV5, RUNX1, THAP11, BCL6, CEBPA, SOX13, ZFX, SIN3A, SMAD3, ZNF770, ERG3, SP5, PRDM10, RARA, CREBBP, ZNF384, RUNX2, CDK6, GATA4, GR, NFIB, ARNT, ZNF48, SMAD4, SP2, SUPT5H, SNRNP70, MED1, TEAD3, CEBPD, C11orf30, ZNF22, RBM22, MAFK, SP1, HNF4A, IKZF5, REST, ZNF479, POU2F3, ASH2L, TCF3, FOXP1, SMC3, STAG1, ETV4, SKI, PPARG, FOXA2, TBL1X, CREM, EBF1, PAF1, ZNF316, MIER2, WT1, ESR2, FOXF1, TCF7, ZNF580, BCL3, HOXB13, KDM1A, YY1, RELA, SP140, ZIC2, HIF1A, GATA3, TAL1, MAX, NRIP1, ZNF143, AGO2, HAND2, CBX2, TLE3, CEBPG, KLF4, NCOA3, NR2F2, KDM5B, TP53, MED, ZNF334, NFKB1, ELF3, PHF5A, KAT8, ARID4B, AR, NFKBIZ, BHLHE40, ZBTB26, HSF1, NCOR1, BRD4, JUND, SCRT1, MAZ, ZZZ3, AHR
  • Target gene symbol (double-evidenced CRMs): GART,URB1,CFAP298,SYNJ1,CFAP298-TCP10L,SON,PAXBP1
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 3
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops
  • Related gene: ENSG00000142207, ENSG00000265590, ENSG00000159079, ENSG00000159082, ENSG00000159086, ENSG00000159131, ENSG00000159140,
  • Related loop: chr21:27500000-27525000~~chr21:32350000-32375000, chr21:29050000-29075000~~chr21:32350000-32375000, chr21:32350000-32375000~~chr21:32600000-32625000, chr21:32350000-32375000~~chr21:32725000-32750000, chr21:32350000-32375000~~chr21:32750000-32775000, chr21:32350000-32375000~~chr21:33525000-33550000, chr21:32350000-32375000~~chr21:34325000-34350000,
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