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Basic information

CohesinDB ID: CDBP00416938

Locus: chr21-32379033-32379799

Data sourse: GSE86191, GSE116344, ENCSR153HNT, GSE83726

Cell type: K-562, RH4, HCT-116

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 90% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "4_Tx": 62%, "5_TxWk": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, NFIA, PGR, XBP1, FOXA1, RBFOX2, LEO1, RXRB, MLL4, ZNF28, HDGF, THRB, NFIC, ATF3, ZFP64, CTCFL, PRDM1, GLYR1, ZNF189, PAX5, TP63, SFPQ, CDX2, ZNF467, MYOG, ZNF629, KLF5, TEAD1, ZNF121, RBM39, SNAI2, ESR1, OCA2, TP73, CTCF, TCF12, JUN, BAF155, EP300, MNT, GATA6, PAX8, PRDM4, IRF4, E2F1, SMC1, TEAD4, PDX1, TFAP2C, GLIS1, POU2F2, CHD8, ZSCAN5D, POU5F1, MYCN, TOP2A, RUNX1T1, ZNF778, ZMYND11, ZBTB17, ZBTB48, ZSCAN5A, STAT1, ZSCAN21, ZNF205, GATAD1, DDX5, ERG, HOXC5, ASCL1, OGG1, ETS1, MYC, SMARCA4, TOP1, RAD21, GRHL3, RXRA, GABPA, STAT3, APC, SOX10, UBN1, NKX3-1, XRCC5, RCOR1, DNMT3B, ARNTL, NR3C1, CEBPB, ESRRA, CREB1, ZBTB11, EZH2, SPI1, ZNF664, EHF, HDAC2, GATA2, SSRP1, MXI1, SMARCA5, NFIL3, NCOA2, ZIM3, RUNX1, CTNNB1, SMC1A, CEBPA, NKX2-2, SIN3A, ZFX, AFF4, SMAD3, ZNF770, TET2, ZNF654, ERG3, ZNF513, TWIST1, PRDM10, CREBBP, ZNF384, ZBTB2, RUNX2, GATA4, PBX4, NRF1, SOX11, DAXX, ARNT, ZNF48, PRDM9, ZEB2, ATF2, NFIB, PBX3, MAFB, SUPT5H, FOS, MED1, TEAD3, SCRT2, ZMYM3, RBM22, MAFK, NIPBL, SP1, BCL11A, HNF4A, REST, ZNF479, RBM25, ZHX1, ASH2L, HNRNPLL, BCOR, FOXP1, PRDM6, SMC3, STAG1, MLLT1, NFATC3, CBFA2T2, PPARG, FOXA2, PAF1, ZNF600, ZNF692, GTF2B, WT1, HOXB13, ZKSCAN1, KDM1A, YY1, RELA, JUNB, SP140, TCF4, HIF1A, ZIC2, OTX2, GATA3, BATF, TAL1, MAX, NRIP1, GATA1, ZNF143, SPIB, HAND2, SP7, NR2F2, NR2F1, TCF7L2, TP53, ZNF334, MYOD1, ARRB1, ARID4B, PAX3-FOXO1, AR, EGLN2, HSF1, ZBTB26, NCOR1, BRD4, JUND, SCRT1, MAZ, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): PAXBP1,HUNK,ITSN1,AP000311.1,IL10RB,CRYZL1,CFAP298-TCP10L,URB1,AP000295.1,SYNJ1,CFAP298,GART

Function elements

Human SNPs: .

Number of somatic mutations (coding): 4

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene: ENSG00000142149, ENSG00000142207, ENSG00000265590, ENSG00000159079, ENSG00000159082, ENSG00000159086, ENSG00000249624, ENSG00000243646, ENSG00000159131, ENSG00000249209, ENSG00000205758, ENSG00000205726,

eachgene

Deatailed information for cohesin site CDBP00416938