- Basic information
- CohesinDB ID: CDBP00416950
- Locus: chr21-32409703-32410211
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Data sourse: GSE206145, GSE67783
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Cell type: RPE, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 28%,
"15_Quies": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, NFIA, TRIM25, NME2, FOXA1, RXRB, MLL4, THAP1, ZBTB44, IKZF3, MORC2, TEAD1, ZNF121, LMO2, OCA2, MED26, HDAC8, ZNF561, ZNF577, PAX8, E2F4, DEK, ZNF528, GATAD2A, JARID2, NANOG, BRD3, ZNF263, POU5F1, CTBP1, ZMYND11, STAT1, SAP130, ERG, ZBTB21, ZBTB8A, EZH1, SMARCA4, UBN1, ZNF398, RCOR1, NR2F6, CEBPB, HNRNPL, CREB1, BMPR1A, GABPB1, ZHX2, KLF17, GATA2, MXD3, FLI1, HCFC1, MXI1, ZNF785, DRAP1, RUNX1, HDAC1, NKX2-2, CEBPA, REPIN1, ZNF654, SMARCC1, PRDM10, ZBTB2, ZBTB10, ATF2, FOXM1, SP2, SMARCB1, GMEB1, PIAS1, NR1H2, EVI1, GSPT2, ARID2, ELL2, HMGB1, CBFA2T2, CREM, CHD2, PAF1, NFATC1, SS18, ZSCAN16, WT1, NEUROD1, JUNB, ZFP36, MAF1, PLAG1, KLF4, ZFP69B, ZBTB6, EGR2, ELF3, RBM14, ARID4B, RXR, EGLN2, ZBTB26, NCOR1, HSF1, ILF3, FOSL1, ZNF660, XBP1, CDK2, ATF3, ZFP64, CBFB, ZSCAN4, TP63, MITF, ZNF467, MAF, ELF1, RBM39, SNAI2, KLF10, CTCF, TAF3, JUN, ZBTB20, MNT, LMO1, RYBP, DPF2, ZNF423, ZNF677, PDX1, TFAP2C, RBPJ, ZNF317, ZBTB17, ZBTB48, ZSCAN21, SRF, ONECUT1, ZNF2, KDM4A, FOXP2, RXRA, NKX3-1, PRDM14, HNRNPH1, VDR, NR3C1, STAT5B, KMT2A, ZBTB11, KLF8, GRHL2, EBF3, ZBTB14, ZNF146, EZH2phosphoT487, AFF4, SOX13, ZNF770, ZNF513, ZNF18, SP3, NFIB, ARNT, DAXX, BACH1, ZNF48, PRDM9, ZEB2, PBX3, NCAPH2, ZNF10, HMGXB4, TEAD3, ZXDB, KLF9, USF1, BCL11A, SP1, ATF7, ASH2L, CTBP2, GLIS2, PRDM6, ZNF623, SMC3, STAG1, STAG2, ZNF394, TRP47, AGO1, MTA3, MAFF, ESR2, ZNF580, KLF7, ZKSCAN1, KDM1A, BRG1, ZIC2, PCGF1, GATA3, TAL1, ZNF143, MTA1, AGO2, CBX2, TP53, ZNF334, ZSCAN22, BRD2, ARRB1, TBX21, RB1, TFIIIC, RNF2, BRD4, PRDM2, JUND, CUX1, ZSCAN23, ZNF468, PGR, FANCL, SOX2, PATZ1, RING1B, UBTF, TFAP4, CHD7, ZNF189, SMARCE1, MZF1, KLF6, NFE2L2, ZNF217, ESR1, ZNF524, KLF1, E2F6, TRIM24, RFX5, ZNF92, GTF2F1, GLIS1, POU2F2, ZSCAN5A, ZMYND8, ERG2, SP4, TBP, HNF4G, HOXC5, OGG1, ETS1, MYC, KLF12, NKX2-1, GABPA, MCRS1, STAT3, IKZF1, INO80, EZH2, SPI1, PCBP1, HDAC2, ZNF76, NCOA2, ETV5, BCL6, SIN3A, ZBTB12, ERG3, NR0B1, CREBBP, ZNF35, RARA, TAF15, ZNF518A, SMAD4, CDK8, ZEB1, ZMYM3, SUPT16H, SREBF2, REST, ARID1A, ZHX1, HNRNPLL, BCOR, FOXP1, AATF, CXXC4, TBL1X, HDAC6, ZNF692, GTF2B, RELA, TARDBP, MAX, TCF7L2, NR2F1, KDM5B, NEUROG2, MYOD1, AR, ZNF324, HEXIM1, DMAP1, AHR, MBD3, FOSL2, ZSCAN5C, SUZ12, RBFOX2, ZNF28, ZFHX2, SFMBT1, ZNF90, INSM2, NFIC, CTCFL, PRDM1, KLF14, ZNF736, ZNF629, KLF5, TRIM28, ETV1, USF2, TCF12, BAF155, EP300, GATA6, E2F1, SMC1, TEAD4, FOXA3, EHMT2, EED, CHD8, BRD1, MYCN, RUNX1T1, CDK7, GATAD1, ZNF341, RAD21, GRHL3, PROX1, APC, XRCC5, ZNF614, NFE2, ZNF639, ZNF750, FEZF1, EHF, IRF1, SREBF1, MRTFB, ZIM3, ATF1, SMC1A, CBX1, SIRT6, ZNF335, ZFX, FIP1L1, SMAD3, CBX8, RUNX2, ZSCAN30, GATA4, OSR2, ZNF184, GR, CDK6, NRF1, SMAD2, PBX4, CHD1, SUPT5H, FOS, MED1, KDM6B, MYB, CEBPD, L3MBTL2, SETDB1, KLF16, NIPBL, ZBTB7A, POU2F3, PHIP, NELFA, FOXA2, RBBP5, ZNF600, MIER2, ZBTB33, CDK9, HOXB13, YY1, ZNF610, SP140, BRCA1, HIF1A, OTX2, ZNF449, GATA1, CEBPG, SP7, NCOA3, NR2F2, ZNF213, BHLHE40, TAF1, ZNF579, ZBTB42, MYNN, CLOCK, MAZ, ZNF24
- Target gene symbol (double-evidenced CRMs): SYNJ1,CFAP298,PAXBP1,CFAP298-TCP10L,EVA1C
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000166979,
ENSG00000265590,
ENSG00000159079,
ENSG00000159082,
ENSG00000159086,
- Related loop:
chr21:32400000-32425000~~chr21:32500000-32525000,
chr21:32400000-32425000~~chr21:32550000-32575000,
chr21:32400000-32425000~~chr21:32575000-32600000,
chr21:32400000-32425000~~chr21:32600000-32625000,
chr21:32400000-32425000~~chr21:32725000-32750000,
chr21:32400000-32425000~~chr21:32825000-32850000,
chr21:32400000-32425000~~chr21:33175000-33200000,
chr21:32412413-32413787~~chr21:32599845-32601920,
chr21:32412549-32415746~~chr21:32568763-32570909,
chr21:32412635-32415974~~chr21:32561117-32563575,
chr21:32412635-32415974~~chr21:32568694-32570973,
chr21:32412745-32415761~~chr21:32568706-32571494,
chr21:32412745-32415761~~chr21:32598994-32601796,
chr21:32413227-32415524~~chr21:32568643-32570980,
chr21:32413259-32415823~~chr21:32568723-32570970,
chr21:32413259-32415823~~chr21:32599838-32601801,
chr21:32413356-32415861~~chr21:32561346-32563661,
chr21:32413356-32415861~~chr21:32568729-32570718,
chr21:32413356-32415861~~chr21:32599851-32601933,
chr21:32413407-32415950~~chr21:32561489-32563438,
chr21:32413407-32415950~~chr21:32568683-32570920,
chr21:32413407-32415950~~chr21:32599840-32601796,
chr21:32413601-32416113~~chr21:32561649-32563602,
chr21:32413601-32416113~~chr21:32568755-32571056,
chr21:32413601-32416113~~chr21:32599842-32601842,
chr21:32413701-32415963~~chr21:32561671-32563639,
chr21:32413701-32415963~~chr21:32599805-32601899,
chr21:32413909-32415933~~chr21:32599809-32601807,
chr21:32413950-32415829~~chr21:32600085-32601819,
chr21:32414014-32416231~~chr21:32568659-32570952,
chr21:32414040-32415387~~chr21:32568752-32570914,