- Basic information
- CohesinDB ID: CDBP00416954
- Locus: chr21-32422799-32425391
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Data sourse: ENCSR000EFJ, GSE67783, GSE138405, GSE126634, GSE206145, GSE152721, GSE85526, GSE206145-NatGen2015, GSE68388, GSE165895
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Cell type: RPE, Hela-Kyoto, Fibroblast, HEKn, IMR-90, HSPC, HAP1, HuCC-T1, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.900
- Subunit: SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 39%,
"5_TxWk": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SMC1A, CBX3, POU5F1, TOP2A, ZBTB48, ZNF30, DUX4, ZNF580, KDM1A, ZNF384, ZNF510, ZNF610, PRDM1, ZNF518A, PAX5, GATA1, IKZF1, RCOR1, ZNF639, CBX2, TRIM28, SETDB1, PAX8, RBM25, TRIM24, ZSCAN29, ZNF280D, RNF2, BCOR, ZNF280A, ZNF554, ZFP82, ZNF24
- Target gene symbol (double-evidenced CRMs): PAXBP1,EVA1C,CFAP298,SYNJ1,CFAP298-TCP10L
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 36
- Number of somatic mutations (non-coding): 7
- Related genes and loops
- Related gene:
ENSG00000166979,
ENSG00000265590,
ENSG00000159079,
ENSG00000159082,
ENSG00000159086,
- Related loop:
chr21:32400000-32425000~~chr21:32500000-32525000,
chr21:32400000-32425000~~chr21:32550000-32575000,
chr21:32400000-32425000~~chr21:32575000-32600000,
chr21:32400000-32425000~~chr21:32600000-32625000,
chr21:32400000-32425000~~chr21:32725000-32750000,
chr21:32400000-32425000~~chr21:32825000-32850000,
chr21:32400000-32425000~~chr21:33175000-33200000,