- Basic information
- CohesinDB ID: CDBP00416955
- Locus: chr21-32425673-32427854
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Data sourse: ENCSR000BLD, GSE72082, ENCSR000BKV, GSE86191, ENCSR501LQA, GSE110061, GSE111913, ENCSR000BLS, GSE105028, GSE101921, ENCSR054FKH, GSE85526, GSE206145-NatGen2015, GSE206145, ENCSR330ELC, GSE165895
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Cell type: RPE, H1-hESC, Fibroblast, HCT-116, HEKn, Hep-G2, A-549, HCAEC, RT-112, K-562, HFFc6, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 7% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.867
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 31%,
"7_Enh": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, PGR, SOX2, FOXA1, PBX2, ZNF28, ZFHX2, NFIC, ZNF362, TP63, MITF, TEAD1, OCA2, MED26, TP73, CTCF, JUN, TCF12, EP300, BAF155, SOX5, E2F1, ZNF528, SMC1, TEAD4, TFAP2C, EED, RBPJ, GLIS1, NANOG, CHD8, BRD3, TOP2A, ZBTB48, SRF, DDX5, ERG2, TBP, ERG, HOXC5, ZNF341, MYC, SMARCA4, RAD21, GABPA, STAT3, XRCC5, APC, IKZF1, RCOR1, HNRNPH1, ARNTL, NR3C1, CEBPB, EZH2, GRHL2, EBF3, EHF, FLI1, SMC1A, SOX13, ZFX, SMAD3, ZNF770, CBX8, ERG3, ZBTB2, ZNF35, ZNF384, RUNX2, OSR2, PBX4, HMGB2, ETV6, PBX3, FOXM1, FOS, CDK8, MED1, TEAD3, KLF9, SETDB1, BCL11A, SP1, REST, ZNF479, PRDM6, PPARG, FOXA2, EBF1, NFATC1, KDM1A, YY1, RELA, JUNB, ZFP36, HIF1A, GATA3, TAL1, MAX, ZNF143, GATA1, HAND2, KLF4, GFI1B, NCOA3, TP53, NFKB1, EGR2, BRD2, AR, YAP1, ZBTB42, RNF2, BRD4, ILF3, JUND, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): EVA1C
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 30
- Number of somatic mutations (non-coding): 10
- Related genes and loops