- Basic information
- CohesinDB ID: CDBP00416964
- Locus: chr21-32442062-32443561
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Data sourse: ENCSR501LQA, ENCSR000ECS, GSE108869, ENCSR330ELC, GSE138405, GSE101921, ENCSR199XBQ, GSE94872, ENCSR193NSH, GSE206145, ENCSR981FDC, ENCSR247LSH, ENCSR767DFK, ENCSR984DZW, ENCSR495WGO, ENCSR217ELF, ENCSR853VWZ, ENCSR956LGB, ENCSR335RKQ, ENCSR000EDE, GSE68388, GSE126990, ENCSR748MVX
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Cell type: RPE, Hela-Kyoto, A-549, HUVEC, HCAEC, HeLa-S3, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 6% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: SMC3,Rad21,SA2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 46%,
"5_TxWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SMC1A, CEBPA, CHD2, PAF1, ZFX, AFF4, XBP1, TOP2A, ZNF30, ZBTB48, SMAD3, STAT1, PCBP2, SP4, TBP, ERG, HOXC5, RELA, ZNF384, JUNB, ETS1, RUNX2, EZH1, GATA4, MYC, CDK6, RAD21, PRDM1, NRF1, GRHL3, SOX11, DAXX, FOXP2, GATA3, HMGB2, HMBOX1, STAT3, MAX, TAL1, FOS, RCOR1, MED1, NR3C1, KLF4, CEBPB, KLF5, TRIM28, CEBPD, TCF7L2, NFE2L2, TP53, OCA2, NFKB1, ZNF22, CTCF, JUN, TCF12, EP300, SP1, AR, GATA6, TAF1, REST, RFX5, FOSL2, ZHX1, BRD4, JUND, E2F1, ZNF528, MAZ, SMC1, SMC3, ELL2, GTF2F1, EED
- Target gene symbol (double-evidenced CRMs): EVA1C
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 18
- Number of somatic mutations (non-coding): 0
- Related genes and loops