- Basic information
- CohesinDB ID: CDBP00416969
- Locus: chr21-32450290-32453267
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Data sourse: ENCSR000EFJ, GSE67783, GSE86191, GSE138405, GSE116868, ENCSR000HPG, GSE111913, GSE105028, GSE101921, GSE206145-NatGen2015, GSE206145, GSE68388, ENCSR199XBQ, GSE126990, GSE165895
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Cell type: RPE, Fibroblast, HCT-116, Hela-Kyoto, MB157, A-549, HCAEC, IMR-90, HSPC, RT-112, HFFc6, HuCC-T1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 7% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.856
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 38%,
"15_Quies": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RELA, NR3C1, BRD4, NFKB1, MAZ, STAT3, FOS
- Target gene symbol (double-evidenced CRMs): CFAP298-TCP10L,EVA1C,CFAP298,AP000295.1,URB1,IL10RB
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 36
- Number of somatic mutations (non-coding): 6
- Related genes and loops
- Related gene:
ENSG00000142207,
ENSG00000166979,
ENSG00000265590,
ENSG00000159079,
ENSG00000249624,
ENSG00000243646,
- Related loop:
chr21:32025000-32050000~~chr21:32450000-32475000,
chr21:32300000-32325000~~chr21:32450000-32475000,
chr21:32450000-32475000~~chr21:32575000-32600000,
chr21:32450000-32475000~~chr21:33275000-33300000,