Deatailed information for cohesin site CDBP00416970

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  • Basic information
  • CohesinDB ID: CDBP00416970
  • Locus: chr21-32455431-32458336
  • Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE104888, ENCSR230ZWH, GSE72082, ENCSR000BSB, ENCSR501LQA, ENCSR000BLY, ENCSR150EFU, GSE121355, GSE25021, ENCSR330ELC, ENCSR000EDW, GSE108869, ENCSR917QNE, GSE165895, GSE67783, GSE86191, GSE138405, GSE76893, GSE101921, GSE206145-NatGen2015, GSE112028, ENCSR199XBQ, ENCSR703TNG, ENCSR895JMI, ENCSR193NSH, ENCSR768DOX, ENCSR000BLS, GSE206145, ENCSR000ECE, ENCSR247LSH, ENCSR981FDC, ENCSR620NWG, ENCSR748MVX, ENCSR767DFK, ENCSR495WGO, ENCSR984DZW, ENCSR217ELF, GSE105004, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, GSE110061, GSE129526, ENCSR000HPG, ENCSR676MJK, GSE111913, ENCSR335RKQ, ENCSR054FKH, ENCSR537EFT, ENCSR000EDE, GSE68388, GSE126990, ENCSR000ECS
  • Cell type: Liver, HuCC-T1, RPE, Fibroblast, HeLa-S3, IMR-90, HFFc6, H1-hESC, SK-N-SH, RT-112, HeLa-Tet-On, MCF-7, Hela-Kyoto, HCT-116, Hep-G2, A-549, HCAEC, HeLa, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 24% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.789
  • Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
  • CTCF binding site: CTCF CTCF motif: True
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 90% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "5_TxWk": 38%, "7_Enh": 25%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, NFIA, FOSL1, PGR, XBP1, HNF1A, FOXA1, HLF, SUZ12, RXRB, MLL4, ZFHX2, TFAP4, ATF3, NFIC, THAP1, CTCFL, CHD7, PRDM1, ZBTB5, ATF4, TP63, ZNF736, SFPQ, CDX2, TEAD1, ZNF121, ELF1, ETV1, SNAI2, KLF6, ZNF26, LMO2, ESR1, HNF1B, MED26, USF2, CTCF, JUN, TCF12, EP300, BAF155, SOX9, DMAP1, E2F1, ZNF528, SMC1, FOXA3, GATAD2A, GTF2F1, RBPJ, TFAP2C, EED, GLIS1, NANOG, CHD8, POU2F2, BRD1, MYCN, ZNF263, BRD3, ZNF317, ZMYND11, ZBTB48, ZSCAN5A, DUX4, ZBTB17, GATAD1, ERG2, HNF4G, ERG, ZNF300, MIER1, MYC, MCM5, SMARCA4, RFX1, HOMEZ, RAD21, GRHL3, RXRA, PROX1, GABPA, STAT3, XRCC5, APC, NKX3-1, ZNF614, MIER3, NR2F6, ZNF639, ARNTL, NR3C1, CEBPB, ESRRA, CREB1, EZH2, GRHL2, TRPS1, GABPB1, SPI1, ZNF786, GATA2, MXD3, SIX2, DRAP1, MXI1, NR2C2, NFIL3, ZNF554, ETV5, RUNX1, THAP11, CTNNB1, SMC1A, ZBTB24, CEBPA, ZNF707, SOX13, ZFX, SIN3A, AFF4, SMAD3, ERG3, CREBBP, RARA, ZNF384, RUNX2, CDK6, OSR2, GR, ARNT, NRF1, NFIB, PBX4, DAXX, ZNF48, SMAD4, PBX3, NR2C1, FOS, SMARCB1, CDK8, HMGXB4, MED1, TEAD3, DIDO1, SCRT2, PIAS1, STAT5A, USF1, SP1, TFAP2A, BCL11A, HNF4A, IKZF5, REST, ASH2L, HNRNPLL, PHIP, TCF3, FOXP1, SMC3, ELL2, STAG1, PAX7, ZNF283, PPARG, FOXA2, CHD2, SS18, PAF1, MIER2, NFATC1, WT1, MAFF, FOXF1, ZNF580, HOXB13, BCL3, KDM1A, YY1, RELA, JUNB, MCM3, SP140, HIF1A, GATA3, TAL1, MAX, NRIP1, ZNF143, GATA1, CBX2, PLAG1, CEBPG, KLF4, NR2F2, TCF7L2, NR2F1, KDM5B, TP53, ZNF334, NFKB1, MYOD1, EGR2, ELF3, BRD2, KAT8, BHLHE40, AR, ZNF579, RXR, ZNF324, EGLN2, HSF1, ZBTB26, NCOR1, BRD4, SCRT1, JUND, RNF2, MAZ, AHR, FOSL2
  • Target gene symbol (double-evidenced CRMs): URB1,EVA1C,CFAP298,IL10RB,AP000295.1,CFAP298-TCP10L
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 147
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops
  • Related gene: ENSG00000142207, ENSG00000166979, ENSG00000265590, ENSG00000159079, ENSG00000249624, ENSG00000243646,
  • Related loop: chr21:32025000-32050000~~chr21:32450000-32475000, chr21:32300000-32325000~~chr21:32450000-32475000, chr21:32450000-32475000~~chr21:32575000-32600000, chr21:32450000-32475000~~chr21:33275000-33300000,
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