Deatailed information for cohesin site CDBP00416971

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  • Basic information
  • CohesinDB ID: CDBP00416971
  • Locus: chr21-32458592-32459810
  • Data sourse: GSE206145, GSE101921, GSE67783, GSE86191
  • Cell type: RPE, HCT-116, HCAEC, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 1% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.956
  • Subunit: SA1,Rad21,SMC1
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 90% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "5_TxWk": 46%, "4_Tx": 23%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, NFIA, FOSL1, PGR, XBP1, HNF1A, FOXA1, HLF, SUZ12, RXRB, MLL4, ZFHX2, TFAP4, ATF3, NFIC, THAP1, CTCFL, CHD7, PRDM1, ZBTB5, ATF4, TP63, ZNF736, SFPQ, CDX2, TEAD1, ZNF121, ELF1, ETV1, SNAI2, KLF6, ZNF26, LMO2, ESR1, HNF1B, MED26, USF2, CTCF, JUN, TCF12, EP300, BAF155, SOX9, DMAP1, E2F1, ZNF528, SMC1, FOXA3, GATAD2A, GTF2F1, RBPJ, TFAP2C, EED, GLIS1, NANOG, CHD8, POU2F2, BRD1, MYCN, ZNF263, BRD3, ZNF317, ZMYND11, ZBTB48, ZSCAN5A, DUX4, ZBTB17, GATAD1, ERG2, HNF4G, ERG, ZNF300, MIER1, MYC, MCM5, SMARCA4, RFX1, HOMEZ, RAD21, GRHL3, RXRA, PROX1, GABPA, STAT3, XRCC5, APC, NKX3-1, ZNF614, MIER3, NR2F6, ZNF639, ARNTL, NR3C1, CEBPB, ESRRA, CREB1, EZH2, GRHL2, TRPS1, GABPB1, SPI1, ZNF786, GATA2, MXD3, SIX2, DRAP1, MXI1, NR2C2, NFIL3, ZNF554, ETV5, RUNX1, THAP11, CTNNB1, SMC1A, ZBTB24, CEBPA, ZNF707, SOX13, ZFX, SIN3A, AFF4, SMAD3, ERG3, CREBBP, RARA, ZNF384, RUNX2, CDK6, OSR2, GR, ARNT, NRF1, NFIB, PBX4, DAXX, ZNF48, SMAD4, PBX3, NR2C1, FOS, SMARCB1, CDK8, HMGXB4, MED1, TEAD3, DIDO1, SCRT2, PIAS1, STAT5A, USF1, SP1, TFAP2A, BCL11A, HNF4A, IKZF5, REST, ASH2L, HNRNPLL, PHIP, TCF3, FOXP1, SMC3, ELL2, STAG1, PAX7, ZNF283, PPARG, FOXA2, CHD2, SS18, PAF1, MIER2, NFATC1, WT1, MAFF, FOXF1, ZNF580, HOXB13, BCL3, KDM1A, YY1, RELA, JUNB, MCM3, SP140, HIF1A, GATA3, TAL1, MAX, NRIP1, ZNF143, GATA1, CBX2, PLAG1, CEBPG, KLF4, NR2F2, TCF7L2, NR2F1, KDM5B, TP53, ZNF334, NFKB1, MYOD1, EGR2, ELF3, BRD2, KAT8, BHLHE40, AR, ZNF579, RXR, ZNF324, EGLN2, HSF1, ZBTB26, NCOR1, BRD4, SCRT1, JUND, RNF2, MAZ, AHR, FOSL2
  • Target gene symbol (double-evidenced CRMs): CFAP298-TCP10L,IL10RB,EVA1C,URB1,CFAP298,AP000295.1
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 6
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops
  • Related gene: ENSG00000142207, ENSG00000166979, ENSG00000265590, ENSG00000159079, ENSG00000249624, ENSG00000243646,
  • Related loop: chr21:32025000-32050000~~chr21:32450000-32475000, chr21:32300000-32325000~~chr21:32450000-32475000, chr21:32450000-32475000~~chr21:32575000-32600000, chr21:32450000-32475000~~chr21:33275000-33300000,
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