- Basic information
- CohesinDB ID: CDBP00416972
- Locus: chr21-32460801-32461622
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Data sourse: GSE206145-NatGen2015, GSE67783, GSE86191
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Cell type: Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 36%,
"15_Quies": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, CBFA2T2, POU2F2, CHD8, ZSCAN5D, MYCN, ZNF263, BRD3, POU5F1, ZFX, WT1, ZBTB48, ZSCAN5A, FOXA1, ZNF112, SMARCA4, GRHL3, SOX11, STAT3, NCOA3, ESR1, ZNF334, SETDB1, TCF12, AR, BRD4, PHIP, ZNF554
- Target gene symbol (double-evidenced CRMs): CFAP298-TCP10L,URB1,CFAP298,AP000295.1,EVA1C,IL10RB
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 12
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000142207,
ENSG00000166979,
ENSG00000265590,
ENSG00000159079,
ENSG00000249624,
ENSG00000243646,
- Related loop:
chr21:32025000-32050000~~chr21:32450000-32475000,
chr21:32300000-32325000~~chr21:32450000-32475000,
chr21:32450000-32475000~~chr21:32575000-32600000,
chr21:32450000-32475000~~chr21:33275000-33300000,