- Basic information
- CohesinDB ID: CDBP00416973
- Locus: chr21-32462635-32464978
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Data sourse: GSE104888, ENCSR230ZWH, GSE72082, ENCSR000BSB, ENCSR501LQA, ENCSR760NPX, ENCSR000BLY, ENCSR150EFU, ENCSR000ECS, GSE131606, ENCSR330ELC, GSE108869, ENCSR000BUC, ENCSR917QNE, ENCSR000EFJ, GSE165895, GSE138405, GSE76893, GSE101921, ENCSR806UKK, GSE206145-NatGen2015, ENCSR199XBQ, GSE94872, ENCSR895JMI, ENCSR193NSH, ENCSR768DOX, GSE206145, ENCSR981FDC, ENCSR247LSH, ENCSR620NWG, ENCSR767DFK, ENCSR495WGO, ENCSR984DZW, ENCSR217ELF, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, GSE131956, GSE129526, ENCSR676MJK, ENCSR335RKQ, ENCSR537EFT, ENCSR000EDE, GSE68388, GSE126990, ENCSR748MVX
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Cell type: RPE, Fibroblast, HCT-116, Hela-Kyoto, Hep-G2, A-549, HUVEC, HCAEC, HeLa-S3, GBM39, IMR-90, SK-N-SH, Liver, HFFc6, HuCC-T1, DKO
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 22% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.822
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 39%,
"7_Enh": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PHIP, SMARCA4
- Target gene symbol (double-evidenced CRMs): CFAP298-TCP10L,URB1,AP000295.1,CFAP298,IL10RB,EVA1C
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 30
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000142207,
ENSG00000166979,
ENSG00000265590,
ENSG00000159079,
ENSG00000249624,
ENSG00000243646,
- Related loop:
chr21:32025000-32050000~~chr21:32450000-32475000,
chr21:32300000-32325000~~chr21:32450000-32475000,
chr21:32450000-32475000~~chr21:32575000-32600000,
chr21:32450000-32475000~~chr21:33275000-33300000,