Deatailed information for cohesin site CDBP00416974

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  • Basic information
  • CohesinDB ID: CDBP00416974
  • Locus: chr21-32465888-32466157
  • Data sourse: GSE138405, ENCSR153HNT
  • Cell type: K-562, Hela-Kyoto
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 0% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.978
  • Subunit: SA1,SA2
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 90% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "5_TxWk": 58%, "15_Quies": 35%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, HMG20A, ZSCAN5C, HNF1A, XBP1, FOXA1, RXRB, MLL4, ZFHX2, TFAP4, ATF3, NFIC, ZC3H8, MITF, ZNF320, CDX2, TEAD1, KLF6, ETV1, NFE2L2, RCOR2, ESR1, OCA2, USF2, JUN, CTCF, TCF12, EP300, SOX9, SOX5, SOX4, TRIM24, RFX5, IRF4, DEK, E2F1, SMC1, ZNF350, TEAD4, FOXA3, ZNF175, GTF2F1, GATAD2A, TFAP2C, EHMT2, MYCN, BRD3, STAT1, ELK4, SRF, GATAD1, SAP130, ERG2, ARID3A, TBP, HNF4G, ERG, HOXC5, OGG1, ETS1, MYC, SMARCA4, HOMEZ, RAD21, LHX2, GRHL3, PROX1, NKX2-1, RXRA, GABPA, STAT3, APC, ZNF614, UBN1, XRCC5, IKZF1, RCOR1, NFE2, NR2F6, ARNTL, NR3C1, CEBPB, CREB1, MRTFA, ZHX2, IRF1, GATA2, ZNF644, SIX2, FLI1, MXI1, ZGPAT, MRTFB, ZNF554, ETV5, RUNX1, CTNNB1, SMC1A, MAFG, CEBPA, BCL6, AFF4, ZFX, SIN3A, SOX13, SMAD3, SP5, SMARCC1, PRDM10, NR0B1, CREBBP, ZNF384, RARA, RUNX2, CDK6, GATA4, NRF1, PBX4, ARNT, DAXX, BACH1, HMGB2, FOXM1, PBX3, FOS, CDK8, SMARCB1, MED1, ICE2, ZEB1, TEAD3, NR1H2, KLF9, C11orf30, MAFK, SP1, NIPBL, HNF4A, REST, ZHX1, ASH2L, PHIP, FOXP1, SMC3, ELL2, ETV4, PPARG, FOXA2, CBX3, CREM, CHD2, SS18, PAF1, MIER2, ZSCAN16, MAFF, ZNF30, TCF7, HOXB13, BCL3, KDM1A, YY1, RELA, JUNB, BRCA1, TCF4, HIF1A, OTX2, GATA3, TAL1, MAX, ZNF143, KLF4, NR2F2, TCF7L2, KDM5B, TP53, NFKB1, EGR2, ELF3, BRD2, BHLHE40, AR, TAF1, ZBTB40, EGR1, HSF1, NCOR1, RNF2, BRD4, JUND, MAZ, ZNF24, ZNF316, FOSL2
  • Target gene symbol (double-evidenced CRMs): IL10RB,CFAP298-TCP10L,EVA1C,URB1,CFAP298,AP000295.1
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 3
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops
  • Related gene: ENSG00000142207, ENSG00000166979, ENSG00000265590, ENSG00000159079, ENSG00000249624, ENSG00000243646,
  • Related loop: chr21:32025000-32050000~~chr21:32450000-32475000, chr21:32300000-32325000~~chr21:32450000-32475000, chr21:32450000-32475000~~chr21:32575000-32600000, chr21:32450000-32475000~~chr21:33275000-33300000,
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