- Basic information
- CohesinDB ID: CDBP00416976
- Locus: chr21-32468636-32469297
-
Data sourse: GSE67783, ENCSR153HNT, GSE86191, GSE73207
-
Cell type: K-562, TF-1, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SMC3
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"5_TxWk": 34%,
"4_Tx": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, FOSL1, POU2F2, BCL6, CBX3, LDB1, CREM, ZNF263, PAF1, ZFX, CTBP1, ZMYND11, MYCN, DUX4, SMAD3, ZSCAN5A, ZBTB48, WT1, TBL1X, XBP1, SUZ12, FOXA1, PBX2, YY1, RELA, JUNB, EZH1, ARID1B, MCM3, SP140, GRHL3, HIF1A, ARNT, PRDM1, OTX2, GATA3, PRDM9, TAL1, CBFA2T3, MAX, ZNF10, GATA1, CDK8, IKZF1, DNMT3B, ZNF467, NCOA3, TRIM28, ZKSCAN8, RBM39, SNAI2, EZH2, OCA2, L3MBTL2, ZNF334, GRHL2, CTCF, BCL11A, SPI1, AR, PAX8, GATA2, ZBTB7A, E2F6, ZBTB42, FLI1, HSF1, NOTCH3, BRD4, MAZ, ZNF528, MRTFB, STAG1, TFAP2C, EED
- Target gene symbol (double-evidenced CRMs): CFAP298-TCP10L,CFAP298,URB1,AP000295.1,IL10RB,EVA1C
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000142207,
ENSG00000166979,
ENSG00000265590,
ENSG00000159079,
ENSG00000249624,
ENSG00000243646,
- Related loop:
chr21:32025000-32050000~~chr21:32450000-32475000,
chr21:32300000-32325000~~chr21:32450000-32475000,
chr21:32450000-32475000~~chr21:32575000-32600000,
chr21:32450000-32475000~~chr21:33275000-33300000,