Deatailed information for cohesin site CDBP00416979

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  • Basic information
  • CohesinDB ID: CDBP00416979
  • Locus: chr21-32472299-32473135
  • Data sourse: GSE67783, ENCSR153HNT, GSE86191
  • Cell type: K-562, HCT-116, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 1% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.967
  • Subunit: SA1,Rad21
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 90% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "5_TxWk": 40%, "15_Quies": 32%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, PGR, XBP1, FOXA1, MLL4, ZFHX2, TFAP4, ATF3, HNRNPUL1, THAP1, PRDM1, TP63, CDC5L, CDX2, TEAD1, ELF1, RBM39, ETV1, KLF6, ESR1, USF2, CTCF, TCF12, JUN, BAF155, EP300, E4F1, MNT, TRIM24, SMC1, TFAP2C, EED, POU2F2, CHD8, NANOG, ZNF263, MYCN, TOP2A, ID3, POU5F1, ZMYND11, MTA2, ZBTB48, ZSCAN5A, STAT1, ERF, ERG2, TBP, HNF4G, ERG, HOXC5, PBX1, ASCL1, MYC, ONECUT1, SMARCA4, RAD21, FOXP2, RXRA, GABPA, STAT3, UBN1, NKX3-1, IKZF1, RCOR1, DNMT3B, DACH1, ZNF750, NR3C1, CEBPB, ESRRA, CREB1, EZH2, GRHL2, FEZF1, ZNF652, EBF3, TRPS1, ZKSCAN5, EHF, IRF1, HDAC2, GATA2, SSRP1, ZSCAN29, FLI1, MXI1, SMARCA5, RELB, NCOA2, RUNX1, AFF4, ZFX, SIN3A, SMAD3, ZNF770, CBX8, ERG3, ZNF513, SMARCC1, CREBBP, ZNF384, RUNX2, GATA4, NRF1, ARNT, PBX4, DAXX, PBX3, CDK8, SNRNP70, MED1, ZMYM3, PIAS1, NR1H2, ZNF22, BCL11A, SP1, NIPBL, HNF4A, ARID2, ARID1A, ZNF479, RBM25, ATF7, ASH2L, HNRNPLL, PHIP, BCOR, FOXP1, TCF3, ZNF623, SMC3, STAG1, MLLT1, CBFA2T2, ZNF316, TBL1X, FOXA2, PPARG, EBF1, SS18, PAF1, WT1, ZBTB33, HOXB13, KDM1A, YY1, RELA, JUNB, NEUROD1, BRG1, SP140, ZFP36, HIF1A, GATA3, TAL1, MAX, GATA1, CBX2, TLE3, KLF4, NCOA3, NR2F2, NR2F1, TCF7L2, KDM5B, TP53, EGR2, ELF3, AR, ZBTB40, RXR, EGLN2, ZNF366, EGR1, HSF1, RNF2, NCOR1, BRD4, JUND, MAZ, AHR, FOSL2
  • Target gene symbol (double-evidenced CRMs): CFAP298-TCP10L,IL10RB,EVA1C,AP000295.1,URB1,CFAP298
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 45
  • Number of somatic mutations (non-coding): 14
  • Related genes and loops
  • Related gene: ENSG00000142207, ENSG00000166979, ENSG00000265590, ENSG00000159079, ENSG00000249624, ENSG00000243646,
  • Related loop: chr21:31275000-31300000~~chr21:32475000-32500000, chr21:32025000-32050000~~chr21:32450000-32475000, chr21:32300000-32325000~~chr21:32450000-32475000, chr21:32450000-32475000~~chr21:32575000-32600000, chr21:32450000-32475000~~chr21:33275000-33300000, chr21:32475000-32500000~~chr21:32575000-32600000,
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