- Basic information
- CohesinDB ID: CDBP00416984
- Locus: chr21-32483950-32485031
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Data sourse: GSE86191, GSE206145-NatGen2015, GSE120943, GSE68388
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Cell type: Fibroblast, HCT-116, Monocytes, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 47%,
"5_TxWk": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NANOG, CHD8, PPARG, PGR, FOXA2, PAF1, SOX2, ZFX, XBP1, ZNF600, SMAD3, NME2, FOXA1, SRF, ERG3, ERG2, TBP, ZKSCAN1, KDM1A, YY1, RELA, CREBBP, ZNF384, ERG, NEUROD1, ATF3, NFIC, SMARCA4, CHD7, RAD21, GRHL3, HIF1A, ARNT, OTX2, HMGB2, NKX2-1, GABPA, ATF2, STAT3, NRIP1, NFE2, ZNF736, CBX2, ESRRA, ETV1, KDM5B, EZH2, ESR1, OCA2, GRHL2, MYOD1, CTCF, EP300, BAF155, AR, PAX3-FOXO1, GATA6, KLF17, HDAC2, GATA2, EGLN2, POU2F3, ASH2L, RNF2, E2F1, MAZ, STAG1, EED
- Target gene symbol (double-evidenced CRMs): TIAM1,CFAP298-TCP10L,EVA1C,CFAP298
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 15
- Number of somatic mutations (non-coding): 0
- Related genes and loops