- Basic information
- CohesinDB ID: CDBP00416987
- Locus: chr21-32491080-32492695
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Data sourse: GSE206145, GSE206145-NatGen2015, GSE67783, GSE86191
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Cell type: RPE, Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: TSS,TES,Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 35%,
"7_Enh": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, FOSL1, ZNF426, ZNF697, SOX2, XBP1, ZNF101, FOXA1, SUZ12, PBX2, MLL4, ZFHX2, HNRNPK, ZNF90, ZFP64, HNRNPUL1, CHD7, PRDM1, PRDM12, MITF, MAF, ZNF629, ETV1, NFE2L2, ESR1, CTCF, JUN, ZNF577, BAF155, EP300, LMO1, SOX5, DPF2, RFX5, E2F1, SMC1, TEAD4, FOXA3, ZNF555, GATAD2A, TFAP2C, EED, NANOG, CHD8, MYCN, ZNF263, CDK7, POU5F1, MTA2, ZMYND11, ZBTB48, ZSCAN5A, STAT1, SAP130, ERG2, SP4, TBP, ZNF300, ERG, ZBTB21, ASCL1, ZBTB8A, ETS1, MYC, SMARCA4, EOMES, RAD21, FOXP2, GABPA, STAT3, XRCC5, NKX3-1, IKZF1, NR2F6, VDR, ARNTL, NR3C1, CEBPB, KMT2A, CREB1, CCAR2, ZBTB11, BMPR1A, ZNF664, HDAC2, GATA2, INTS13, FLI1, MXI1, RELB, MRTFB, ZIM3, ZC3H11A, ETV5, RUNX1, BCL6, MAFG, HDAC1, SOX13, ZFX, POU4F2, SIN3A, AFF4, SMAD3, ZNF654, ERG3, SP5, SMARCC1, RARA, ZNF384, RUNX2, DAXX, BACH1, ZNF781, ZNF48, SMAD4, ZNF518A, CBFA2T3, PBX3, SP2, FOS, MED1, TEAD3, ZXDB, MYB, SCRT2, PIAS1, ZNF558, ZNF680, KLF9, TBX5, MAFK, SP1, BCL11A, USF1, HNF4A, REST, ZBTB7A, ATF7, ASH2L, CTBP2, FOXP1, ZNF623, SMC3, ZNF34, STAG2, MLLT1, STAG1, NFATC3, ZNF394, TRP47, ZNF316, FOXA2, RBBP5, MIER2, WT1, HOXB13, ZNF580, KDM1A, RELA, JUNB, ZNF266, ZNF510, ZFP36, HIF1A, PCGF1, GATA3, TAL1, MAX, ZNF143, GATA1, TLE3, ZFP69B, SP7, GFI1B, NR2F2, ZNF791, TP53, PKNOX1, ZNF213, EGR2, ZNF140, ELF3, T, BRD2, PHF5A, TBX21, ARID4B, AR, BHLHE40, TAF1, EGR1, ZBTB26, RNF2, IKZF2, BRD4, SCRT1, JUND, MAZ, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): CFAP298,TIAM1,CFAP298-TCP10L,EVA1C
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 15
- Number of somatic mutations (non-coding): 5
- Related genes and loops