- Basic information
- CohesinDB ID: CDBP00416989
- Locus: chr21-32494469-32496274
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Data sourse: ENCSR000BLD, ENCSR000EFJ, GSE206145-GSE177045, GSE67783, GSE72082, GSE86191, GSE138405, ENCSR000HPG, GSE206145, GSE206145-NatGen2015, ENCSR000EDE, GSE126990, GSE108869, ENCSR000ECS, GSE165895
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Cell type: MCF-7, H1-hESC, RPE, Fibroblast, HCT-116, Hela-Kyoto, HeLa-S3, IMR-90, HSPC, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 12% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.889
- Subunit: NIPBL,SA1,Rad21,SMC3ac,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 45%,
"7_Enh": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: BRD4, RNF2, CBX8
- Target gene symbol (double-evidenced CRMs): CFAP298-TCP10L,TIAM1,EVA1C,CFAP298
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 132
- Number of somatic mutations (non-coding): 44
- Related genes and loops