- Basic information
- CohesinDB ID: CDBP00416990
- Locus: chr21-32498609-32500453
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Data sourse: ENCSR000EFJ, ENCSR230ZWH, GSE86191, GSE131956, GSE165895, ENCSR000HPG, ENCSR000BLY, GSE206145, GSE101921, GSE206145-NatGen2015, ENCSR153HNT, GSE68388, GSE83726, GSE94872, ENCSR917QNE
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Cell type: RPE, Fibroblast, HCT-116, RH4, HUVEC, HCAEC, GBM39, IMR-90, SK-N-SH, K-562, Liver, HuCC-T1, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 11% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.856
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 45%,
"7_Enh": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, SIN3A, FOXA1, ERG, YY1, RELA, JUNB, NFIC, RUNX2, RAD21, RXRA, OTX2, GATA3, TAL1, FOXM1, MAX, PBX3, FOS, MED1, ETV1, JUN, TCF12, CTCF, EP300, AR, GATA2, REST, BRD4, JUND, FOXP1, E2F1, SMC1, TEAD4, STAG2, FOSL2
- Target gene symbol (double-evidenced CRMs): SYNJ1,CFAP298-TCP10L,TIAM1,EVA1C,CFAP298
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 15
- Number of somatic mutations (non-coding): 5
- Related genes and loops
- Related gene:
ENSG00000156299,
ENSG00000166979,
ENSG00000265590,
ENSG00000159079,
ENSG00000159082,
- Related loop:
chr21:31275000-31300000~~chr21:32475000-32500000,
chr21:32400000-32425000~~chr21:32500000-32525000,
chr21:32475000-32500000~~chr21:32575000-32600000,
chr21:32500000-32525000~~chr21:32600000-32625000,
chr21:32500000-32525000~~chr21:33025000-33050000,