- Basic information
- CohesinDB ID: CDBP00416999
- Locus: chr21-32517976-32518345
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Data sourse: GSE206145, GSE206145-NatGen2015, GSE67783
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Cell type: RPE, Fibroblast, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 53%,
"5_TxWk": 38%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, NFIA, FOSL1, PGR, ZNF496, ZSCAN5C, XBP1, FOXA1, HLF, PBX2, ZFHX2, HDGF, ATF3, NFIC, INSM2, ZNF362, ATF4, SMARCE1, JMJD1C, ZNF629, ZNF121, TRIM28, KLF6, SNAI2, NFE2L2, LMO2, SMAD5, MLL, OCA2, CTCF, JUN, TCF12, EP300, KLF1, DPF2, IRF4, RFX5, TRIM24, DEK, E2F1, SMC1, TEAD4, GTF2F1, GLIS1, POU2F2, CHD8, ZNF263, MYCN, TOP2A, CTBP1, ZMYND11, ZBTB17, ZBTB48, STAT1, SRF, ERG2, TBP, ERG, HOXC5, SMARCC2, ETS1, MYC, EZH1, SMARCA4, ARID1B, FOXP2, RAD21, GRHL3, ZNF24, NKX2-1, BATF3, STAT3, XRCC5, IKZF1, RCOR1, NFE2, ZNF639, NR3C1, CEBPB, CREB1, KLF8, ZHX2, ELF4, SPI1, ZNF664, EHF, IRF1, HDAC2, GATA2, ZNF146, FLI1, MXI1, SMARCA5, HCFC1R1, NFIL3, MRTFB, ATF1, RUNX1, AFF4, ZFX, POU4F2, SMAD3, TET2, ERG3, SMARCC1, PRDM10, ZNF384, ZNF35, NFYC, TAF15, RUNX2, CDK6, GATA4, OSR2, ZNF184, PBX4, NRF1, ATF2, ZEB2, PBX3, SMARCB1, CDK8, CHD1, FOS, MED1, CEBPD, ZMYM3, PIAS1, MAFK, BCL11A, REST, ZBTB7A, RBM25, ATF7, ZNF548, BCOR, PRDM6, SMC3, ELL2, STAG1, NFATC3, PPARG, FOXA2, MTA3, CREM, MEIS1, PAF1, SS18, ZNF600, CHD2, CBX3, WT1, HOXB13, ZNF580, KDM1A, YY1, RELA, TARDBP, JUNB, BRG1, SP140, ZFP36, ZIC2, SKIL, HIF1A, GATA3, TAL1, MAX, ZNF143, GATA1, CEBPG, ZFP69B, TCF7L2, TP53, PKNOX1, ZNF334, EGR2, ELF3, BHLHE40, AR, EGLN2, ZNF280D, HSF1, RNF2, BRD4, JUND, MAZ, ZSCAN23, BRCA1, FOSL2
- Target gene symbol (double-evidenced CRMs): SYNJ1,EVA1C,CFAP298-TCP10L,CFAP298
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops