- Basic information
- CohesinDB ID: CDBP00417012
- Locus: chr21-32551895-32552608
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Data sourse: GSE206145, GSE206145-NatGen2015, GSE67783, GSE86191
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Cell type: RPE, Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Mau2,SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 73%,
"14_ReprPCWk": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MED1, RELA, DPF2, OGG1, ZKSCAN1, ZFX, PRDM1, TEAD4, WT1, ZBTB48, BRD4, JUN, PAX5, CTCF, BCL11A, NFE2, FOSL2
- Target gene symbol (double-evidenced CRMs): EVA1C,SMIM11A,MIS18A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 7
- Related genes and loops