- Basic information
- CohesinDB ID: CDBP00417018
- Locus: chr21-32566765-32568083
-
Data sourse: ENCSR000BLD, GSE67783, GSE86191, GSE111913, GSE206145, GSE206145-NatGen2015, ENCSR153HNT, GSE73207
-
Cell type: RPE, H1-hESC, Fibroblast, HCT-116, TF-1, RT-112, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,SMC3
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 38%,
"5_TxWk": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, ZNF394, NFIA, ZNF426, ZNF697, ZNF263, LDB1, ZBTB48, WT1, STAT1, ZNF101, ZNF654, ZBTB21, RELA, ZBTB8A, NFIC, ZNF266, ZFP64, RUNX2, MYC, CHD7, EZH1, NFIB, PRDM12, ZNF781, ZNF518A, TAL1, GATA1, TLE3, ZNF629, TRIM28, MYB, ZBTB11, ZNF680, KMT2A, ZNF213, ZNF140, ZNF577, BCL11A, ZNF664, AR, GATA2, FOXP1, MAZ, ZNF623, SMC3, ZNF555, ZNF34
- Target gene symbol (double-evidenced CRMs): SMIM11A,EVA1C,MIS18A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 7
- Related genes and loops
- Related gene:
ENSG00000159055,
ENSG00000166979,
ENSG00000205670,
- Related loop:
chr21:32250000-32275000~~chr21:32550000-32575000,
chr21:32275000-32300000~~chr21:32550000-32575000,
chr21:32391823-32394318~~chr21:32568639-32570686,
chr21:32400000-32425000~~chr21:32550000-32575000,
chr21:32401983-32404518~~chr21:32561692-32563664,
chr21:32401983-32404518~~chr21:32568620-32570676,
chr21:32401987-32404521~~chr21:32561668-32563604,
chr21:32401987-32404521~~chr21:32568752-32570914,
chr21:32402003-32404663~~chr21:32561174-32563689,
chr21:32402003-32404663~~chr21:32568752-32570717,
chr21:32402041-32404495~~chr21:32568771-32570910,
chr21:32402043-32404526~~chr21:32561117-32563575,
chr21:32402043-32404526~~chr21:32568694-32570973,
chr21:32402050-32404562~~chr21:32561335-32563466,
chr21:32402050-32404562~~chr21:32568741-32570718,
chr21:32402058-32404410~~chr21:32561685-32563661,
chr21:32402064-32404444~~chr21:32568763-32570866,
chr21:32402099-32404537~~chr21:32561649-32563602,
chr21:32402099-32404537~~chr21:32568755-32571056,
chr21:32402112-32404476~~chr21:32561642-32563675,
chr21:32402112-32404476~~chr21:32568659-32570952,
chr21:32402211-32404532~~chr21:32561346-32563661,
chr21:32402220-32404493~~chr21:32568752-32570984,
chr21:32402227-32404394~~chr21:32568753-32570714,
chr21:32402351-32404483~~chr21:32561228-32563461,
chr21:32402421-32404494~~chr21:32561489-32563438,
chr21:32402421-32404494~~chr21:32568683-32570920,
chr21:32402478-32404275~~chr21:32568878-32570910,
chr21:32402530-32404222~~chr21:32568734-32570738,
chr21:32402531-32404281~~chr21:32568877-32570702,
chr21:32402537-32404397~~chr21:32568723-32570970,
chr21:32402544-32404481~~chr21:32568763-32570909,
chr21:32402553-32404518~~chr21:32561671-32563639,
chr21:32402553-32404518~~chr21:32568691-32570731,
chr21:32402571-32404278~~chr21:32569132-32570716,
chr21:32402573-32404309~~chr21:32561693-32563678,
chr21:32402573-32404309~~chr21:32568716-32570850,
chr21:32402575-32404404~~chr21:32561712-32563519,
chr21:32402578-32404394~~chr21:32568853-32570643,
chr21:32402588-32404419~~chr21:32568769-32570666,
chr21:32402590-32404484~~chr21:32568776-32570930,
chr21:32402599-32404105~~chr21:32568593-32570609,
chr21:32402604-32404315~~chr21:32568733-32570864,
chr21:32402611-32404103~~chr21:32568778-32570670,
chr21:32402633-32404083~~chr21:32568855-32570579,
chr21:32412549-32415746~~chr21:32568763-32570909,
chr21:32412635-32415974~~chr21:32561117-32563575,
chr21:32412635-32415974~~chr21:32568694-32570973,
chr21:32412745-32415761~~chr21:32568706-32571494,
chr21:32413227-32415524~~chr21:32568643-32570980,
chr21:32413259-32415823~~chr21:32568723-32570970,
chr21:32413356-32415861~~chr21:32561346-32563661,
chr21:32413356-32415861~~chr21:32568729-32570718,
chr21:32413407-32415950~~chr21:32561489-32563438,
chr21:32413407-32415950~~chr21:32568683-32570920,
chr21:32413601-32416113~~chr21:32561649-32563602,
chr21:32413601-32416113~~chr21:32568755-32571056,
chr21:32413701-32415963~~chr21:32561671-32563639,
chr21:32414014-32416231~~chr21:32568659-32570952,
chr21:32414040-32415387~~chr21:32568752-32570914,
chr21:32523530-32525270~~chr21:32568683-32570920,
chr21:32550000-32575000~~chr21:34350000-34375000,