Browse_each

Basic information

CohesinDB ID: CDBP00417019

Locus: chr21-32569005-32571301

Data sourse: ENCSR230ZWH, ENCSR000FAD, ENCSR000BSB, ENCSR000EGW, GSE131606, ENCSR330ELC, ENCSR000BUC, ENCSR000DYE, ENCSR917QNE, GSE115602, GSE139435, GSE93080, GSE67783, GSE86191, GSE101921, ENCSR806UKK, GSE51234, GSE120943, ENCSR198ZYJ, GSE112028, GSE130135, ENCSR199XBQ, GSE94872, ENCSR895JMI, GSE118494, ENCSR000EEG, ENCSR338DUC, ENCSR247LSH, GSE105004, ENCSR676MJK, GSE155324, ENCSR054FKH, GSE83726, ENCSR748MVX, ENCSR000ECS, GSE131577, ENCSR000BLD, GSE38411, GSE104888, GSE126634, GSE103477, GSE108869, GSE143937, GSE138405, GSE135093, GSE106870, ENCSR193NSH, GSE206145, GSE85526, ENCSR000ECE, ENCSR620NWG, ENCSR767DFK, ENCSR984DZW, GSE55407, ENCSR000BTQ, GSE129526, ENCSR537EFT, ENCSR760NPX, ENCSR000BLY, ENCSR150EFU, GSE121355, GSE111537, GSE25021, ENCSR000EAC, GSE122299, GSE115250, GSE76893, GSE145327, GSE76815, ENCSR000BMY, ENCSR000EHX, ENCSR635OSG, GSE97394, ENCSR217ELF, GSE38395, GSE131956, GSE110061, ENCSR000HPG, GSE111913, ENCSR335RKQ, ENCSR000EDE, GSE50893, ENCSR481YWD, GSE206145-GSE177045, GSE72082, ENCSR501LQA, GSE116868, ENCSR404BPV, GSE105028, ENCSR000EDW, GSE165895, ENCSR000EFJ, ENCSR000BTU, ENCSR000DZP, ENCSR000BKV, GSE152721, GSE206145-NatGen2015, GSE138105, ENCSR703TNG, GSE116344, GSE98367, ENCSR768DOX, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, GSE155828, ENCSR981FDC, ENCSR807WAC, ENCSR495WGO, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, ENCSR153HNT, GSE68388, GSE126990

Cell type: MDM, RH4, GM10847, GM2610, SLK, CVB-hiPSC, GM19240, HSPC, CVI-hiPSC, Liver, GP5d, Transformed-RPE1, TC-32, HuCC-T1, B-cell, H9-hESC, GM2630, HMEC, Fibroblast, RPE, HEKn, THP-1, Ishikawa, GM12890, HeLa-S3, hLCL, GM2255, IMR-90, BCBL-1, K-562, GM18486, DKO, HFFc6, GM18526, H1-hESC, SNYDER, Monocytes, GM18505, Leukemia-SEM, MB157, Lymphoblast, GM12878, GM12891, GM2588, GBM39, SK-N-SH, GM19239, HeLa-Tet-On, GM19193, RT-112, HAP1, GM19099, HUES64, Macrophage, GM12892, MCF-7, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, Neurons-H1, A-549, HUVEC, HCAEC, GM19238, HeLa, TC-71, OCI-AML-3, GM18951

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 79% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.189

Subunit: NIPBL,SA1,Rad21,SMC1,SMC3ac,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 90% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "2_TssAFlnk": 21%, "1_TssA": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, NFIA, FOXA1, RXRB, MLL4, KDM3A, MORC2, PAX5, TEAD1, ZNF121, LMO2, OCA2, MED26, PITX3, ZNF561, SOX5, E2F4, DEK, ZNF674, ZNF528, RFX3, KMT2B, GATAD2A, JARID2, BRD3, ZNF263, POU5F1, CTBP1, STAT1, SAP130, ERG, ZBTB8A, SMARCA4, FOXK2, UBN1, ZNF398, RCOR1, NR2F6, CEBPB, HNRNPL, CREB1, GABPB1, ZHX2, MIXL1, KLF17, GATA2, ZNF644, MXD3, FLI1, DRAP1, MXI1, HCFC1, RELB, RUNX1, HDAC1, NKX2-2, CEBPA, ZNF654, SP5, TRIM22, SMARCC1, PRDM10, ZBTB2, TFDP1, ZBTB10, ATF2, FOXM1, SP2, SMARCB1, ZNF331, PIAS1, SMAD1, EVI1, GSPT2, ARID2, IKZF5, ELL2, NFATC3, CBX3, CREM, CHD2, NFATC1, PAF1, SS18, ZSCAN16, WT1, CREB3L1, NEUROD1, ZFP36, PLAG1, KLF4, BCL11B, ZFP69B, MED, EGR2, ELF3, ARID4B, RXR, EGLN2, ZNF366, ZBTB26, HSF1, NCOR1, SCRT1, ILF3, ZNF660, ZNF101, KDM4B, PBX2, ATF3, ZFP64, RUNX3, CBFB, TP63, ZSCAN4, MITF, INTS11, MAF, JMJD1C, ELF1, RBM39, SNAI2, JUN, TAF3, CTCF, ZBTB20, MNT, RYBP, DPF2, IRF4, ZNF423, TFAP2C, RBPJ, MLX, MTA2, ZSCAN21, ZBTB17, ZBTB48, NONO, SRF, NBN, PBX1, KDM4A, ZNF2, FOXP2, HOMEZ, RXRA, NKX3-1, MIER3, HNRNPH1, VDR, NR3C1, STAT5B, KMT2A, CCAR2, TBL1XR1, KLF8, GRHL2, EBF3, KDM5A, ZBTB14, SMARCA5, NFIL3, THAP11, ZBTB24, EZH2phosphoT487, SOX13, AFF4, ZNF770, SP3, ARNT, ZNF48, ZEB2, NFYA, NCAPH2, ZNF10, HMGXB4, TEAD3, DIDO1, ZXDB, ZNF680, U2AF1, TAF7, KLF9, BCL11A, SP1, ATF7, ASH2L, CTBP2, PCGF2, GLIS2, SMC3, STAG1, MLLT1, STAG2, ZNF394, TRP47, AGO1, MTA3, MAFF, ZNF580, ZKSCAN1, KDM1A, BRG1, ZIC2, PCGF1, GATA3, TAL1, ZNF143, AGO2, CBX2, TP53, ZSCAN22, PHOX2B, BRD2, PHF5A, KAT8, ARRB1, TBX21, EGR1, RB1, TFIIIC, RNF2, JUND, BRD4, PGR, SOX2, PATZ1, RING1B, UBTF, TFAP4, SIN3B, CHD7, ZNF444, MXD4, ZNF189, SMARCE1, RLF, KLF6, NFE2L2, SAP30, ESR1, ZNF217, KLF1, ZNF260, SOX4, E2F6, TRIM24, RFX5, GTF2F1, GLIS1, POU2F2, ZNF778, KDM4C, ZSCAN5A, ZMYND8, ERG2, SP4, TBP, HOXC5, OGG1, SMARCC2, ETS1, MYC, GABPA, STAT3, IKZF1, GFI1, INO80, EZH2, ZNF652, SPI1, HDAC2, INTS13, ZNF76, ZNF554, ETV5, BCL6, SIN3A, ZFP37, ERG3, RARA, CREBBP, ZNF35, NFYC, TAF15, SMAD4, CDK8, ZEB1, ZMYM3, RBM22, HNF4A, REST, ZHX1, HNRNPLL, BCOR, FOXP1, AATF, CXXC4, PPARG, TBL1X, ZNF692, GTF2B, ZNF30, ZNF574, RELA, TARDBP, SKIL, MGA, MAX, GFI1B, NR2F1, TCF7L2, KDM5B, MYOD1, T, AR, ZNF324, HEXIM1, DMAP1, AHR, ZNF391, HMG20A, SUZ12, RBFOX2, ZFHX2, SFMBT1, INSM2, CTCFL, MECOM, CDX2, ZNF629, TRIM28, BCLAF1, ETV1, RCOR2, USF2, TCF12, EP300, BAF155, GATA6, PRDM4, SOX6, E2F1, SMC1, TEAD4, FOXA3, ZNF175, EED, CHD8, BRD1, MYCN, CDK7, ID3, RUNX1T1, GATAD1, ARID3A, USP7, MIER1, ZNF341, RAD21, GRHL3, PROX1, XRCC5, ZNF614, NFE2, ZNF639, FEZF1, TFE3, IRF1, ZGPAT, MRTFB, ATF1, PTBP1, CBX1, SMC1A, SIRT6, ZNF335, ZFX, FIP1L1, SMAD3, IRF2, NOTCH1, RUNX2, SMAD2, GATA4, OSR2, ZNF184, CDK6, NRF1, PBX4, CHD1, MED1, KDM6B, MYB, SCRT2, CEBPD, ZNF3, L3MBTL2, SETDB1, KLF16, NIPBL, ZBTB7A, POU2F3, PHIP, TCF3, SKI, NELFA, KLF13, FOXA2, RBBP5, E2F8, ZNF600, MIER2, FOXF1, CDK9, HOXB13, YY1, ZNF610, SP140, HIF1A, ZNF449, GATA1, CEBPG, SP7, ZNF512, ZNF687, NFKBIZ, BHLHE40, TAF1, ZNF579, ZBTB40, ZBTB42, MAZ, ZNF24

Target gene symbol (double-evidenced CRMs): MIS18A,EVA1C,SMIM11A,URB1,CFAP298-TCP10L

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 15

Related genes and loops

Related gene: ENSG00000159055, ENSG00000142207, ENSG00000166979, ENSG00000265590, ENSG00000205670,

eachgene

Deatailed information for cohesin site CDBP00417019