- Basic information
- CohesinDB ID: CDBP00417020
- Locus: chr21-32571677-32572067
-
Data sourse: GSE206145-NatGen2015, GSE111913, GSE67783, GSE86191
-
Cell type: RT-112, Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SA2,SMC1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"5_TxWk": 36%,
"15_Quies": 35%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MEIS2, KDM4B, FOXA1, RBFOX2, RXRB, PBX2, HDGF, ATF3, KLF5, ELF1, TRIM28, KLF6, SNAI2, CTCF, JUN, E4F1, SOX5, DPF2, TRIM24, E2F1, FOXA3, GATAD2A, RBPJ, TFAP2C, POU2F2, ZNF263, POU5F1, TOP2A, ZBTB17, ZBTB48, DDX5, SAP130, HOMEZ, RAD21, GRHL3, GABPA, XRCC5, ZNF614, ZNF639, ZNF750, CREB1, EZH2, GABPB1, HDAC2, DRAP1, ATF1, ETV5, CC2D1A, SOX13, ZFX, ERG3, CBX8, SP5, RARA, ZNF184, NRF1, ARNT, ZNF48, ATF2, SMAD4, HMGXB4, TEAD3, L3MBTL2, IKZF5, ATF7, POU2F3, BCOR, CBX3, MTA3, FOXA2, RBBP5, CREM, EBF1, WT1, KDM1A, AHR, BRG1, SP140, MAX, KLF4, TP53, ELF3, ARID4B, AR, BRD4, JUND, MAZ, ZNF24, ZNF316
- Target gene symbol (double-evidenced CRMs): CFAP298-TCP10L,MIS18A,SMIM11A,EVA1C
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000159055,
ENSG00000166979,
ENSG00000265590,
ENSG00000205670,
- Related loop:
chr21:22775000-22800000~~chr21:32575000-32600000,
chr21:31175000-31200000~~chr21:32575000-32600000,
chr21:31725000-31750000~~chr21:32575000-32600000,
chr21:31850000-31875000~~chr21:32575000-32600000,
chr21:32250000-32275000~~chr21:32550000-32575000,
chr21:32275000-32300000~~chr21:32550000-32575000,
chr21:32275000-32300000~~chr21:32575000-32600000,
chr21:32300000-32325000~~chr21:32575000-32600000,
chr21:32375000-32400000~~chr21:32575000-32600000,
chr21:32391823-32394318~~chr21:32568639-32570686,
chr21:32400000-32425000~~chr21:32550000-32575000,
chr21:32400000-32425000~~chr21:32575000-32600000,
chr21:32401983-32404518~~chr21:32568620-32570676,
chr21:32401987-32404521~~chr21:32568752-32570914,
chr21:32402003-32404663~~chr21:32568752-32570717,
chr21:32402041-32404495~~chr21:32568771-32570910,
chr21:32402043-32404526~~chr21:32568694-32570973,
chr21:32402050-32404562~~chr21:32568741-32570718,
chr21:32402064-32404444~~chr21:32568763-32570866,
chr21:32402099-32404537~~chr21:32568755-32571056,
chr21:32402112-32404476~~chr21:32568659-32570952,
chr21:32402220-32404493~~chr21:32568752-32570984,
chr21:32402227-32404394~~chr21:32568753-32570714,
chr21:32402421-32404494~~chr21:32568683-32570920,
chr21:32402478-32404275~~chr21:32568878-32570910,
chr21:32402530-32404222~~chr21:32568734-32570738,
chr21:32402531-32404281~~chr21:32568877-32570702,
chr21:32402537-32404397~~chr21:32568723-32570970,
chr21:32402544-32404481~~chr21:32568763-32570909,
chr21:32402553-32404518~~chr21:32568691-32570731,
chr21:32402571-32404278~~chr21:32569132-32570716,
chr21:32402573-32404309~~chr21:32568716-32570850,
chr21:32402578-32404394~~chr21:32568853-32570643,
chr21:32402588-32404419~~chr21:32568769-32570666,
chr21:32402590-32404484~~chr21:32568776-32570930,
chr21:32402599-32404105~~chr21:32568593-32570609,
chr21:32402604-32404315~~chr21:32568733-32570864,
chr21:32402611-32404103~~chr21:32568778-32570670,
chr21:32402633-32404083~~chr21:32568855-32570579,
chr21:32412549-32415746~~chr21:32568763-32570909,
chr21:32412635-32415974~~chr21:32568694-32570973,
chr21:32412745-32415761~~chr21:32568706-32571494,
chr21:32413227-32415524~~chr21:32568643-32570980,
chr21:32413259-32415823~~chr21:32568723-32570970,
chr21:32413356-32415861~~chr21:32568729-32570718,
chr21:32413407-32415950~~chr21:32568683-32570920,
chr21:32413601-32416113~~chr21:32568755-32571056,
chr21:32414014-32416231~~chr21:32568659-32570952,
chr21:32414040-32415387~~chr21:32568752-32570914,
chr21:32450000-32475000~~chr21:32575000-32600000,
chr21:32475000-32500000~~chr21:32575000-32600000,
chr21:32523530-32525270~~chr21:32568683-32570920,
chr21:32550000-32575000~~chr21:34350000-34375000,