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Basic information

CohesinDB ID: CDBP00417024

Locus: chr21-32580005-32580573

Data sourse: GSE86191, GSE98367, GSE111913, GSE206145, GSE206145-NatGen2015, GSE120943, ENCSR153HNT

Cell type: RPE, Fibroblast, HCT-116, Monocytes, RT-112, K-562, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.922

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 90% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 40%, "14_ReprPCWk": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, LDB1, ZFX, WT1, ZBTB48, FOXA1, TET2, CBX8, DDX5, HOXB13, PRDM10, ERG, YY1, BMI1, ATF3, SMARCA4, RFX1, MCM3, SP140, ZFP36, PAX5, CDK8, CBX2, CEBPB, EZH2, CTCF, AR, HDAC2, ZBTB7A, ASH2L, RNF2, HSF1, MAZ, STAG1, AHR

Target gene symbol (double-evidenced CRMs): SCAF4,EVA1C,URB1,HUNK,CFAP298-TCP10L,TIAM1,MIS18A

Function elements

Human SNPs: .

Number of somatic mutations (coding): 39

Number of somatic mutations (non-coding): 13

Related genes and loops

Related gene: ENSG00000156299, ENSG00000156304, ENSG00000142149, ENSG00000159055, ENSG00000142207, ENSG00000166979, ENSG00000265590,

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Deatailed information for cohesin site CDBP00417024