- Basic information
- CohesinDB ID: CDBP00417026
- Locus: chr21-32583026-32584806
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Data sourse: GSE67783, GSE86191, GSE132649, GSE206145, GSE206145-NatGen2015, ENCSR153HNT
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Cell type: RPE, T-47D, Fibroblast, HCT-116, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 41%,
"14_ReprPCWk": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF384, TRP47, OGG1, ZBTB48, ZBTB33, DDX5
- Target gene symbol (double-evidenced CRMs): MIS18A,EVA1C,SCAF4,URB1,TIAM1,CFAP298-TCP10L,HUNK
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 150
- Number of somatic mutations (non-coding): 50
- Related genes and loops
- Related gene:
ENSG00000156299,
ENSG00000156304,
ENSG00000142149,
ENSG00000159055,
ENSG00000142207,
ENSG00000166979,
ENSG00000265590,
- Related loop:
chr21:22775000-22800000~~chr21:32575000-32600000,
chr21:31175000-31200000~~chr21:32575000-32600000,
chr21:31725000-31750000~~chr21:32575000-32600000,
chr21:31850000-31875000~~chr21:32575000-32600000,
chr21:31872680-31874526~~chr21:32577373-32579026,
chr21:32275000-32300000~~chr21:32575000-32600000,
chr21:32300000-32325000~~chr21:32575000-32600000,
chr21:32375000-32400000~~chr21:32575000-32600000,
chr21:32400000-32425000~~chr21:32575000-32600000,
chr21:32402135-32404476~~chr21:32577078-32579215,
chr21:32402391-32404315~~chr21:32577279-32579257,
chr21:32402609-32404463~~chr21:32577411-32579232,
chr21:32450000-32475000~~chr21:32575000-32600000,
chr21:32475000-32500000~~chr21:32575000-32600000,