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Basic information

CohesinDB ID: CDBP00417027

Locus: chr21-32585090-32585613

Data sourse: ENCSR230ZWH, GSE67783, ENCSR153HNT, GSE86191

Cell type: K-562, Liver, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 90% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 43%, "5_TxWk": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, TRP47, POU2F2, SMC1A, TBL1X, ZNF263, MYCN, RUNX1T1, NFATC1, ZFX, ZSCAN5D, XBP1, ASH1L, WT1, ZBTB48, ZSCAN5A, FOXA1, TET2, ERG3, SUZ12, CBX8, ERG2, HOXB13, ZNF18, ZFHX2, ERG, YY1, BCL3, HDGF, ZBTB2, RELA, ATF3, SMARCA4, SP140, ARNT, ZFP36, ZNF48, PBX3, PAX5, ZNF143, IKZF1, CBX2, SRSF3, ELF1, EZH2, LMO2, OCA2, L3MBTL2, EGR2, STAT5A, CTCF, ZFP91, SPI1, E4F1, SP1, HNF4A, GATA6, IRF1, ZBTB40, HDAC2, ZBTB7A, FLI1, RNF2, HNRNPLL, TCF3, MAZ, ZNF24, STAG1, AHR

Target gene symbol (double-evidenced CRMs): HUNK,EVA1C,SCAF4,MIS18A,CFAP298-TCP10L,URB1,TIAM1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 13

Number of somatic mutations (non-coding): 5

Related genes and loops

Related gene: ENSG00000156299, ENSG00000156304, ENSG00000142149, ENSG00000159055, ENSG00000142207, ENSG00000166979, ENSG00000265590,

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Deatailed information for cohesin site CDBP00417027