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Basic information

CohesinDB ID: CDBP00417028

Locus: chr21-32586300-32587559

Data sourse: GSE67783, GSE72082, ENCSR000BLS, GSE206145, ENCSR153HNT

Cell type: K-562, RPE, HSPC, Hep-G2

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 90% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 38%, "5_TxWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: ZNF621, XBP1, FOXA1, SUZ12, RBFOX2, HDGF, ATF3, THAP1, ZBTB5, ZNF444, ATF4, MXD4, SMARCE1, ZNF736, CDC5L, ELF1, BCLAF1, TEAD1, MCM7, TRIM28, NFE2L2, LMO2, ESR1, ZIK1, USF2, CTCF, TCF12, JUN, E4F1, MNT, DPF2, E2F6, TRIM24, ZNF407, E2F4, ZNF410, ZNF776, ZNF280A, TEAD4, ZNF175, GTF2F1, EHMT2, YBX1, CHD8, ZSCAN5D, POU5F1, MYCN, TOP2A, MTA2, ASH1L, ZBTB48, NONO, SRF, DDX5, NBN, PHB2, ERG, MIER1, MYC, EZH1, SMARCA4, RFX1, ARID1B, RAD21, FOXK2, GABPA, IKZF1, NFE2, RCOR1, ZNF639, YBX3, ARHGAP35, GABPB1, HES1, IRF1, HDAC2, GATAD2B, MXD3, SMARCA5, EP400, SALL2, CC2D1A, RUNX1, HDAC1, ZFX, ZNF473, NFXL1, TET2, ZNF18, ZBTB2, PRPF4, ZNF184, ARNT, ATF2, SNIP1, ETV6, SUPT5H, TEAD3, C11orf30, NCOA1, L3MBTL2, MAFK, USF1, BCL11A, HNF4A, ARID2, REST, ZBTB7A, ATF7, BCOR, AATF, MLLT1, STAG1, NFATC3, NCOA4, FOXA2, AGO1, CBX3, CHD2, NFATC1, WT1, ZNF662, ZKSCAN1, CREB3L1, YY1, RELA, ZNF148, AHR, NEUROD1, ZNF282, MCM3, SP140, HIF1A, ZNF311, MGA, MAF1, MAX, TAL1, ZNF143, MTA1, GATA1, PLAG1, ZNF592, NR2F2, ZNF544, EGR2, BHLHE40, TAF1, ZBTB40, HSF1, RNF2, NCOR1, ZBTB26, JUND, MAZ, ZNF24, ZNF316

Target gene symbol (double-evidenced CRMs): URB1,TIAM1,CFAP298-TCP10L,MIS18A,EVA1C,HUNK,SCAF4

Function elements

Human SNPs: .

Number of somatic mutations (coding): 7

Number of somatic mutations (non-coding): 7

Related genes and loops

Related gene: ENSG00000156299, ENSG00000156304, ENSG00000142149, ENSG00000159055, ENSG00000142207, ENSG00000166979, ENSG00000265590,

eachgene

Deatailed information for cohesin site CDBP00417028